Comparison of intraocular pressure post penetrating keratoplasty vs Descemet's stripping endothelial keratoplasty.

Objective: To compare the effect of Descemet's stripping endothelial keratoplasty (DSEK) with penetrating keratoplasty (PKP) on intraocular pressure (IOP) and use of ocular antihypertensives.

Design: Retrospective cohort study.

Participants: Thirty-five eyes in 33 patients undergoing PKP and 43 eyes in 38 patients undergoing DSEK were included in the analysis.

Primary intraocular lymphoma arising during methotrexate treatment of temporal arteritis.

Case Report: Primary intraocular lymphoma arose over a period of 9 months in the left eye of an 81-year-old woman who was blind in both eyes from temporal arteritis. During this period, she was treated with prednisone and methotrexate. Following a sudden total hyphema, the eye was enucleated.

Are subjects satisfied with the informed consent process? A survey of research participants.

Objective: Letters of information (LOI) for clinical trials are becoming longer and more complicated. We investigated patients' perspectives of their ability to understand the information presented during a clinical trial. Satisfaction with and motivation for participation in clinical trials were also ascertained.