Publications by authors named "David O' Sullivan"

The aim of this study was to compare the short-term estimated hospital costs and charges for open, laparoscopic, and robot-assisted sacral colpopexy. The null hypothesis was that there would be no difference in costs and charges. Fifteen comparable cases were reviewed for demographics, surgical information, and estimated hospital charges and costs and then compared with analysis of variance.

View Article and Find Full Text PDF

The census tract-based residential segregation literature rests on problematic assumptions about geographic scale and proximity. We pursue a new tract-free approach that combines explicitly spatial concepts and methods to examine racial segregation across egocentric local environments of varying size. Using 2000 census data for the 100 largest U.

View Article and Find Full Text PDF

Aims: The relationship of detrusor overactivity (DO) to neuromuscular causes is well established, but a connection to kidney function has not yet been studied. We sought to evaluate whether patients with DO have differences in estimated glomerular filtration rate (eGFR).

Methods: After Institutional Review Board approval, we collected data from all patients who underwent urodynamic testing in our office from September 1, 2006 to February 28, 2007 and calculated eGFR using the equation derived from the Modification of Diet in Renal Disease (MDRD) study.

View Article and Find Full Text PDF

Objective: The North American Menopause Society (NAMS) provides a forum through which researchers can present scientific abstracts. After presenting an abstract, the goal is to publish the research as a full-length article. The objective for this study was to determine the publication rate of abstracts presented at NAMS meetings.

View Article and Find Full Text PDF

Neural stem cells (NSCs) have the potential to be used for the treatment of Parkinson's disease (PD), as they can be expanded, manipulated and differentiated in vitro to generate dopaminergic neurones which are suitable for transplantation. Since NSCs have a tendency to follow an astrocytic lineage after differentiation in vitro, researchers are investigating ways to induce a neuronal phenotype in these cells. In this study, the human immunodeficiency virus 1 (HIV-1) transactivator of transcription (TAT) protein transduction domain (PTD) system was used in an attempt to promote neuronal differentiation in rodent NSCs.

View Article and Find Full Text PDF

Objective: To estimate the prevalence of cervical human papillomavirus (HPV) and cytological abnormalities while addressing demographic and reproductive variables in a sample of rural Nigerian patients.

Methods: In March 2004, a medical project was conducted in Okene, Nigeria. The obstetrics/gynecology team collected demographics of 231 patients and 199 ThinPrep Pap smears (Cytyc, Marlborough, MA), which were analyzed cytologically and for the presence of HPV DNA.

View Article and Find Full Text PDF

Objective: The objective was to estimate the prevalence of malignancy or dysplasia in cervical polyps.

Methods: A convenience sample was identified by retrospectively searching the Hartford Hospital pathology database for cases of endocervical polyps removed from January 1, 1999, through January 31, 2006. The presence of malignancy, dysplasia, atypia, and other modifiers was recorded along with demographic information, including age, race/ethnicity, residence, and the ordering practitioner.

View Article and Find Full Text PDF

Objective: The purpose of this study was to compare gender, humanistic qualities or technical competence (HQTC), and age when an obstetrician-gynecologist is selected.

Study Design: Participants saw photographs (2 women, 2 men) without descriptors then the same photographs with descriptors. To test whether HQTC were more important than gender, the men in the photographs were given HQTC descriptors.

View Article and Find Full Text PDF

Objective: Breast arterial calcifications (BACs) are common but unreported findings on screening mammograms. This study correlated mammographically detected BACs with coronary artery disease (CAD) risk factors and a history of atherosclerotic cardiovascular disease (ASCVD), estimating the relative risk of ASCVD in patients with BACs.

Design: Women arriving for breast cancer screening mammography gave their consent to complete a questionnaire and to allow their mammograms to be analyzed independently for the presence of BACs by certified radiologists, who were blinded to the results of the questionnaire.

View Article and Find Full Text PDF

The purpose of this study was to evaluate whether community-dwelling women can reliably identify infected urine samples. A convenience sample of 25 women judged six urine samples. Of these, two were normal, two contained culture-proven infections, and two were intentionally abnormal because of ingestion of asparagus or vitamins.

View Article and Find Full Text PDF

Objective: To bring further understanding to the relationship between hormonal therapy (HT) and breast arterial calcification (BAC).

Methods: Of women arriving for breast cancer screening mammography, 1995 consented to complete a survey and have their mammograms analyzed for the presence of BAC. The survey assessed HT use and major risk factors for CAD.

View Article and Find Full Text PDF

Objective: The objective of this study was to determine risk factors for intra-operative cystotomy during TVT and whether this affects surgical outcome and morbidity.

Study Design: Charts of 340 women who underwent TVT were reviewed. Those who had a cystotomy during the procedure (cases) were compared with those without (controls) for the variables: age, race, parity, body mass index (BMI), TVT with or without other procedures, previous pelvic surgery, blood loss, length of catheter drainage, UTI, and voiding dysfunction.

View Article and Find Full Text PDF

We investigated whether women with and without anterior vaginal wall prolapse have voiding differences. Women (n=109) who presented to a urogynecology practice were categorized into two groups based on anterior vaginal wall prolapse: stages 0 and 1 and stages 2, 3, and 4. Women with prolapse were older than the women without prolapse but the groups were otherwise similar demographically.

View Article and Find Full Text PDF

The aim of the study is to assess satisfaction with urogynecology education among obstetrics and gynecology residents. An Internet-based survey was designed to obtain a cross-sectional sample of third- and fourth-year residents. Didactic and surgical training as well as perceived surgical competency were assessed.

View Article and Find Full Text PDF

Objective: To assess the qualities and attributes desired in menopause clinicians.

Design: Women > or =45 years of age (n=72) were surveyed about the qualities and attributes desired in their physician. Surveys were performed in physician waiting rooms in Connecticut.

View Article and Find Full Text PDF

Objective: To determine if there is a significant difference in outcomes of clinical trials funded by industry or not of antimuscarinic medications used to treat overactive bladder (OAB) symptoms and detrusor overactivity (DOA).

Methods: A Medline search was conducted from January 1966 to June 2003 to identify human clinical trials of oxybutynin and tolterodine published in English. Randomized controlled trials on subjects aged > or = 16 years who were being treated with oxybutynin or tolterodine for OAB symptoms or DOA; 24 studies were identified.

View Article and Find Full Text PDF

Objective: To evaluate the prevalence and histologic outcomes of patients with atypical glandular cells of undetermined significance (AGUS), diagnosed by Pap test, and concurrent risk factors.

Data Sources: A PubMed/MEDLINE/Ovid HealthStar search of the English literature was conducted from January 1988 through March 2004.

Methods Of Study Selection: The search criteria included the terms "atypical glandular cells of undetermined significance," "AGUS," or "AGC.

View Article and Find Full Text PDF

The objective of this study was to assess differences in menopausal symptoms between postmenopausal (PM) Hispanic (H) and PM Caucasian (C) women. This was a prospective survey. Data from a convenience sample of 404 PM women (50% H, 50% C) were evaluated.

View Article and Find Full Text PDF

Objective: Studies analyzing menopause symptoms have primarily focused on white women of higher socioeconomic status. With an aging population and a longer life expectancy, we can anticipate a significant rise in women presenting with menopause symptoms and issues related to quality of life. It is important to know whether current data regarding menopause symptoms are applicable to all women seeking care.

View Article and Find Full Text PDF

The noninvasive differentiation between ischemic and nonischemic cardiomyopathy is frequently difficult. We examined the clinical value of stress electrocardiographic gated (ECG-gated) single-photon emission computed tomography (SPECT) to identify ischemic cardiomyopathy and detect coronary artery disease (CAD) in 164 patients without known CAD, ejection fraction < or =40% by ECG-gated SPECT, and subsequent coronary angiography. Summed stress, rest, and difference scores were measured from the SPECT studies, and regional wall motion variance was calculated from the ECG-gated images.

View Article and Find Full Text PDF