Publications by authors named "David N Hala"

There is a paucity of information on the levels of PAHs and PCBs in the deep-sea (≥200 m). In this study, the body-burdens of 16 PAHs and 29 PCBs were measured in: Actinaria (sea anemones), Holothuroidea (sea cucumber), Pennatulacea (sea pens), and Crinoidea (sea lilies) in the deep Gulf of Mexico. All epibenthic species were collected at depths of approximately 2000 m.

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The fathead minnow (Pimephales promelas) is an OECD-proposed test species routinely used in reproductive toxicity trials with suspected endocrine-disrupting compounds (EDCs). The basic fecundity, endocrinology, and histopathology of reproductively active male and female fathead minnows has been well characterized, but there are few studies of the utility of male sperm concentration and motility as endpoints for use in reproductive trials. The purpose of this study was to (1) characterize the baseline sperm concentration and motility of pair-breeding male fathead minnows over their spawning cycle and (2) determine whether a repeated and nondestructive sperm sampling protocol would influence the baseline fecundity of the fish.

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The effects of Clofibric acid (a persistent environmental metabolite of Clofibrate, a human pharmaceutical), on Fathead minnows were studied. Fibrates are used to prevent cardiovascular disease through their antilipidemic activity. In a series of experiments, in which fish were exposed to waterborne Clofibric acid, no convincing, reproducible antilipidemic effects were observed.

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