Acetylation of the histone variant H2A.Z (H2A.Zac) occurs at active regulatory regions associated with gene expression.
View Article and Find Full Text PDFCancer research has been heavily geared towards genomic events in the development and progression of cancer. In contrast, metabolic regulation, such as aberrant metabolism in cancer, is poorly understood. Alteration in cellular metabolism was once regarded simply as a consequence of cancer rather than as playing a primary role in cancer promotion and maintenance.
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