Peripheral Inflammation Links with the Severity of Clinical Phenotype in Spinocerebellar Ataxia 2.

Background: The role of peripheral inflammation in spinocerebellar ataxia type 2 (SCA2) is unknown.

Objective: The objective of this study was to identify peripheral inflammation biomarkers and their relationship with the clinical and molecular features.

Methods: Blood cell count-derived inflammatory indices were measured in 39 SCA2 subjects and their matched controls.