Publications by authors named "David Miranda"

Structural health monitoring applications have gained significant attention in recent research, particularly in the study of the mechanical-electrical properties of materials such as cement-based composites. While most researchers have focused on the piezoresistive properties of cement-based composites under compressive stress, exploring the electrical impedance of such materials can provide valuable insights into the relationship between their mechanical and electrical characteristics. In this study, we investigated the connection between the mechanical properties and electrical impedance of cement-based composites modified with Au nanoparticles.

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  • * The study, called PROACTIVE-HF, assessed the safety and effectiveness of this monitoring method in 456 patients with chronic heart failure across various centers in the US and Europe.
  • * Results showed a 6-month event rate of 0.15 hospitalizations or deaths per patient, far below the goal of 0.43, with a very high safety rate for the device.
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Previous research has commonly evaluated preference stability over time and across multiple preference assessment administrations. No studies have evaluated shifts in preference across consecutive rounds of a single preference assessment, where rounds refer to each time the experimenter resets the stimulus-presentation array. The purpose of the present study was to examine the stability of stimulus selections across successive rounds of a multiple-stimulus-without-replacement (MSWO) preference assessment with different classes of stimuli for children with autism.

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  • Parenchymal analysis can assess breast cancer risk by examining mammography texture features, but the underlying mechanisms are still unclear.
  • Evidence of field cancerization suggests pre-cancerous changes occur in tissue, potentially affecting its biochemical and optical properties.
  • A study using virtual breast models found that as field cancerization altered tissue properties, certain texture features in mammography images showed significant differences, indicating potential for early cancer detection.
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Objectives: The purpose of this paper is to describe a university program, Spartan Caregiver Support, that provided free on-demand telehealth services to caregivers of people with autism during the State of Michigan's 2020 Stay-at-Home order.

Method: Participants ( = 17) were caregivers of people with autism residing within the State of Michigan. Participants engaged with program members over video-conference technology, where participants received specific advice to support social and behavioral needs.

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The Biological Condition Gradient (BCG) is a conceptual model used to describe incremental changes in biological condition along a gradient of increasing anthropogenic stress. As coral reefs collapse globally, scientists and managers are focused on how to sustain the crucial structure and functions, and the benefits that healthy coral reef ecosystems provide for many economies and societies. We developed a numeric (quantitative) BGC model for the coral reefs of Puerto Rico and the US Virgin Islands to transparently facilitate ecologically meaningful management decisions regarding these fragile resources.

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Objectives: We sought to evaluate interobserver concordance among experienced electrocardiogram (ECG) readers in predicting acute thrombotic coronary occlusion (ATCO) in the context of abnormal metabolic milieu (AMM) following resuscitated out of hospital cardiac arrest (OHCA).

Methods: OHCA patients with initial shockable rhythm who underwent invasive coronary angiography (ICA) were included. AMM was defined as one of: pH < 7.

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The oral administration of Tribulus terrestris and Lepidium meyenii extracts on reproductive, biochemical and body parameters was evaluated in rats. Thirty-six male Wistar rats weighting 210 ± 18 g were divided into six experimental groups (n = 6). Each group received, daily for 28 days, different solutions: T.

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Background And Objectives: The computerized analysis of mammograms for the development of quantitative biomarkers is a growing field with applications in breast cancer risk assessment. Computerized image analysis offers the possibility of using different methods and algorithms to extract additional information from screening and diagnosis images to aid in the assessment of breast cancer risk. In this work, we review the algorithms and methods for the automated, computerized analysis of mammography images for the task mentioned, and discuss the main challenges that the development and improvement of these methods face today.

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TiO electrochemical biosensors represent an option for biomolecules recognition associated with diseases, food or environmental contaminants, drug interactions and related topics. The relevance of TiO biosensors is due to the high selectivity and sensitivity that can be achieved. The development of electrochemical biosensors based on nanostructured TiO surfaces requires knowing the signal extracted from them and its relationship with the properties of the transducer, such as the crystalline phase, the roughness and the morphology of the TiO nanostructures.

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Objectives: Chronic critical illness (CCI) is a phenotype that occurs frequently in patients with severe injury. Previous work has suggested that inflammatory changes leading to CCI occur early following injury. However, the modifiable factors associated with CCI are unknown.

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Objectives: The initial 12 lead electrocardiogram (ECG) following return of spontaneous circulation (ROSC) after out-of-hospital cardiac arrest (OHCA), is often disregarded by clinicians in ability to predict acute thrombotic coronary occlusion (ATCO) due to markedly abnormal metabolic milieu (AMM). We sought to evaluate the accuracy of initial vs. follow-up ECG prior to invasive coronary angiography (ICA) to predict ATCO following resuscitated OHCA.

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Background: Hypertension, hyperglycemia, dyslipidemia, overweight, obesity, and tobacco (smoking, chewing, and vaping), together with a pro-inflammatory and procoagulant state, are the main risk factors related to atherosclerotic cardiovascular disease.

Objective And Methods: A group of experts from the Americas, based on their clinical expertise in cardiology, cardiovascular prevention, and cardiometabolic (CM) diseases, joined together to develop these practical recommendations for the optimal evaluation and treatment of residual CM risk factors in Latin America, using a modified Delphi methodology (details in electronic TSI) to generate a comprehensive CM risk reduction guideline, and through personalized medicine and patient-centered decision, considering the cost-benefit ratio The process was well defined to avoid conflicts of interest that could bias the discussion and recommendations.

Results: Residual risk reduction should consider therapeutic options adapted to specific patient needs, based on five treatment objectives: triglyceride-rich lipoproteins, inflammation, impaired glucose metabolism, high blood pressure, and prothrombotic status.

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Study Objective: Ventricular paced rhythm is thought to obscure the electrocardiographic diagnosis of acute coronary occlusion myocardial infarction. Our primary aim was to compare the sensitivity of the modified Sgarbossa criteria (MSC) to that of the original Sgarbossa criteria for the diagnosis of occlusion myocardial infarction in patients with ventricular paced rhythm.

Methods: In this retrospective case-control investigation, we studied adult patients with ventricular paced rhythm and symptoms of acute coronary syndrome who presented in an emergency manner to 16 international cardiac referral centers between January 2008 and January 2018.

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Purpose: To compare the number of admissions, clinical features and therapeutic outcomes of patients treated for acute ST-segment elevation myocardial infarction (STEMI), before and after the COVID-19 pandemic state of emergency in Peru.

Methods: Observational analytical study of retrospective cohorts, derivated from the PEruvian Registry of ST-segment Elevation Myocardial Infarction II (PERSTEMI II). We compared the patients treated for STEMI, between 45 days before and during the first 45 days of the COVID-19 state of emergency in Peru.

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Fungal endocarditis is a rare clinical entity. This report describes an unusual case of fungal endocarditis caused by infection with in a 20-year-old immunocompetent man who received the diagnosis 1 year following biological aortic valve replacement. ().

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Background: Cardiovascular intensive care units have evolved in time, from being exclusively dedicated to the care of myocardial infarction patients, to treating complex and varied cardiovascular pathologies. We do not have data about the characteristics of patients in cardiovascular intensive care units in Peru.

Material And Methods: We prospectively evaluated the clinical and epidemiological characteristics of patients admitted between July and November 2018 to the intensive and intermediate care unit of the National Cardiovascular Institute INCOR in Lima, Peru.

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Background: Cognitive impairment is common in older patients with heart failure (HF), leading to higher 30-day readmission rates than those without cognitive impairment.

Objectives: The aim of this study was to determine whether increased readmissions in older adults with cognitive impairment are related to HF severity and whether readmissions can be modified by caregiver inclusion in nursing discharge education.

Methods: This study used prospective quality improvement program of cognitive testing and inclusion of caregivers in discharge education with chart review.

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In recent years, mammographic image analysis has shown great potential for breast cancer risk assessment. The aim of risk assessment is to predict how likely a woman is to develop breast cancer in the future. Several studies suggest that computerized parenchymal analysis of mammograms can be utilized as an independent imaging biomarker of breast cancer.

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Group A streptococcal infections are a major cause of benign and deadly human infections with their most destructive manifestation taking the form of necrotizing soft tissue infections (NSTIs) and toxic shock syndrome. The mainstays of treatment have not changed since antibiotic agents were added to the standard of early diagnosis and aggressive surgical debridement, and the mortality rate continues to be staggering. In the age of targeted medicine, there is undoubtedly a need for a more precise approach to treating this spectrum of aggressive diseases.

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The 12-lead electrocardiogram (ECG) remains the most immediately accessible and widely used initial diagnostic tool for guiding management in patients with suspected myocardial infarction (MI). Although the development of high-sensitivity cardiac troponin assays has improved the rule-in and rule-out and risk stratification of acute MI without ST elevation, the immediate management of the subset of acute MI with acute coronary occlusion depends on integrating clinical presentation and ECG findings. Careful interpretation of the ECG might yield subtle features suggestive of ischemia that might facilitate more rapid triage of patients with subtle acute coronary occlusion or, conversely, in identification of ST-elevation MI mimics (pseudo ST-elevation MI patterns).

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Objective: To determine the epidemiological characteristics, treatment, reperfusion strategies and in-hospital adverse events of patients with ST elevation myocardial infarction in Peru.

Methods: Observational, prospective multicentre study in patients over 18 years admitted to hospital with a diagnosis of ST elevation myocardial infarction.

Results: A total of 396 patients were enrolled in the registry during February 2016 to February 2017.

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Background: Targeted Temperature Management (TTM) improves outcomes after cardiac arrest but may affect the QT and QTc intervals which could increase the chance of subsequent arrhythmia. We report here the effects of TTM on both computer-derived and manually calculated QT and QTc as well as the relationship of the length of the QTc and serious arrhythmia in a retrospective single-center experience.

Methods: 193 patients undergoing TTM for cardiac arrest were studied.

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