Dengue Virus NS1 Uses Scavenger Receptor B1 as a Cell Receptor in Cultured Cells.

The dengue virus NS1 is a multifunctional protein that forms part of replication complexes. NS1 is also secreted, as a hexamer, to the extracellular milieu. Circulating NS1 has been associated with dengue pathogenesis by several mechanisms.

Neither an Optimist Nor a Pessimist Be: Mistaken Expectations Lower Well-Being.

This article speaks to the classic view that mental health requires accurate self-perception. Using a representative British sample ( = 1,601) it finds that, as measured by two established well-being indicators, those with mistaken expectations, whether optimistic or pessimistic, do worse than realists. We index unrealistic optimism as the difference between financial expectations and financial realizations measured annually over 18 years.

Why are there more same-sex than opposite-sex dizygotic twins?

Study Question: Are there more same-sex (SS) than opposite-sex (OS) pairs among dizygotic twins?

Summary Answer: In violation of Weinberg's Differential Rule, there are significantly more SS than OS pairs among dizygotic twins in nationally representative samples both in the UK and the USA.

What Is Known Already: Since at least 1874, twin researchers have assumed that dizygotic twins were equally likely to be SS or OS (later formalized as Weinberg's Differential Rule). However, recent research on the sex-specific nature of breastmilk suggests that OS twins might be at a developmental disadvantage relative to SS twins.