Publications by authors named "David Megvinet"
Article Synopsis
- Impaired energy production in heart tissue is common in cardiac diseases, prompting the need for an efficient way to assess mitochondrial function using small heart tissue samples.
- This study utilized high-resolution respirometry to analyze fresh human cardiac muscle homogenates, demonstrating that this method is quicker and requires less tissue compared to traditional mitochondrial isolation techniques.
- The findings indicate that the method provides reliable and reproducible results, with preserved mitochondrial integrity and comparable bioenergetics between atrial and ventricular heart tissue.
