Publications by authors named "David M J Tax"

Cardiovascular disease (CVD) is the most important cause of morbidity and mortality worldwide. Early detection, prevention or even prediction is of pivotal importance to reduce the burden of cardiovascular disease and its associated costs. Low cost, consumer-grade smartwatches have the potential to revolutionize cardiovascular medicine by enabling continuous monitoring of heart rate and activity.

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  • The study explored the potential of supervised machine learning applied to ECG data for real-time sleep monitoring in pediatric intensive care, which is currently not available.
  • Researchers analyzed polysomnography recordings from 90 non-critically ill children, developing various machine learning models to classify sleep states based on derived features from the ECG data.
  • Results showed that the models achieved moderate to good accuracy, especially in classifying two and three sleep states, with the XGBoost model performing best overall, highlighting the method's promise for bedside use.
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  • The study aims to create a straightforward index for sleep classification using electroencephalography data to address sleep disruption in pediatric intensive care units where real-time monitoring is unavailable.! -
  • A retrospective analysis was performed at Erasmus MC Sophia Children's Hospital on polysomnography recordings from non-critically ill children between 2017 and 2021, evaluating sleep patterns across various age groups and frequency bands.! -
  • The results indicated a strong performance of the developed sleep index, particularly with a gamma to delta power ratio, achieving balanced accuracy rates of up to 0.92 for two-state classifications in different age categories, suggesting it could facilitate automated sleep monitoring for children aged 6 months to 18 years.!
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  • Untargeted metabolomics (UM) is being used to screen for inborn errors of metabolism (IEM), and this study analyzed various outlier detection methods for identifying patient profiles.
  • Different outlier detection methods showed varying levels of effectiveness in detecting IEM, with some methods performing consistently well across datasets, while others excelled in more balanced sample conditions.
  • The study highlights the importance of using PCA transformations to enhance method performance and notes that while some methods succeeded in detecting 90% of IEM patients without false positives, further refinements are needed for reliable clinical application.
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Assessment of cultural heritage assets is now extremely important all around the world. Non-destructive inspection is essential for preserving the integrity of artworks while avoiding the loss of any precious materials that make them up. The use of Infrared Thermography is an interesting concept since surface and subsurface faults can be discovered by utilizing the 3D diffusion inside the object caused by external heat.

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  • Meteorites offer insights into the Solar System's origins, with Antarctica being the best location to find them due to stranding zones.
  • Researchers used advanced datasets and machine learning to identify approximately 600 meteorite-rich areas across Antarctica, achieving over 80% accuracy.
  • This new, data-driven method indicates that less than 15% of surface meteorites have been collected, helping streamline future recovery efforts.
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The main challenges of age estimation from facial expression videos lie not only in the modeling of the static facial appearance, but also in the capturing of the temporal facial dynamics. Traditional techniques to this problem focus on constructing handcrafted features to explore the discriminative information contained in facial appearance and dynamics separately. This relies on sophisticated feature-refinement and framework-design.

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We present a new model for multivariate time-series classification, called the hidden-unit logistic model (HULM), that uses binary stochastic hidden units to model latent structure in the data. The hidden units are connected in a chain structure that models temporal dependencies in the data. Compared with the prior models for time-series classification such as the hidden conditional random field, our model can model very complex decision boundaries, because the number of latent states grows exponentially with the number of hidden units.

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In multiple instance learning, objects are sets (bags) of feature vectors (instances) rather than individual feature vectors. In this paper, we address the problem of how these bags can best be represented. Two standard approaches are to use (dis)similarities between bags and prototype bags, or between bags and prototype instances.

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The cell of origin of the five subtypes (I-V) of germ cell tumors (GCTs) are assumed to be germ cells from different maturation stages. This is (potentially) reflected in their methylation status as fetal maturing primordial germ cells are globally demethylated during migration from the yolk sac to the gonad. Imprinted regions are erased in the gonad and later become uniparentally imprinted according to fetal sex.

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A common way to model multi-class classification problems is by means of Error-Correcting Output Codes (ECOC). Given a multi-class problem, the ECOC technique designs a code word for each class, where each position of the code identifies the membership of the class for a given binary problem. A classification decision is obtained by assigning the label of the class with the closest code.

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A computer-aided detection (CAD) system is presented for the localization of interstitial lesions in chest radiographs. The system analyzes the complete lung fields using a two-class supervised pattern classification approach to distinguish between normal texture and texture affected by interstitial lung disease. Analysis is done pixel-wise and produces a probability map for an image where each pixel in the lung fields is assigned a probability of being abnormal.

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LESS: a model-based classifier for sparse subspaces.

IEEE Trans Pattern Anal Mach Intell

September 2005

In this paper, we specifically focus on high-dimensional data sets for which the number of dimensions is an order of magnitude higher than the number of objects. From a classifier design standpoint, such small sample size problems have some interesting challenges. The first challenge is to find, from all hyperplanes that separate the classes, a separating hyperplane which generalizes well for future data.

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