Publications by authors named "David M Hood"
Objective: To investigate the effects of ketamine hydrochloride on the analgesic effects of tramadol hydrochloride in horses with signs of pain associated with naturally occurring chronic laminitis.
Animals: 15 client-owned adult horses with chronic laminitis.
Procedures: Each horse received tramadol alone or tramadol and ketamine in a randomized, crossover study (≥ 2 months between treatments).
Objective: To evaluate patterns of digital cushion (DC) displacement that occur in response to vertical loading of the distal portion of the forelimb in horses. Sample Population-Forelimbs from 10 horses with normal feet.
Procedure: Patterns of DC displacement induced by in vitro vertical limb loading were determined.
Objective: To describe architectural changes along the dorsal laminar interface of the equine foot.
Sample Population: 6 macroscopically normal forefeet obtained from 6 equine cadavers.
Procedure: Histologic sections of 8 evenly spaced, proximal to distal, samples of the dorsal laminar interface were photographed, digitized, and examined for differences in architecture.
Objective: To describe submural histopathologic changes attributable to peracute laminitis in horses.
Animals: 20 adult horses.
Procedure: A concurrent-control design was used to compare laminar lesions in 10 horses subjected to carbohydrate-induced laminitis with laminar characteristics of 10 sex- and aged-matched control horses with normal feet.
Objective: To determine whether systemic immunologic hyperreactivity exists in horses with chronic laminitis, compared with responses for nonlaminitic horses.
Animals: 7 nonlaminitic horses and 7 CL horses.
Procedure: In experiment 1, intradermal testing (IDT) was performed on 7 nonlaminitic and 7 CL horses to evaluate the response to a combination of 70 allergens at 15 and 30 minutes and 4 and 24 hours after injection.
Objective: To evaluate the short-term effects of 4 therapeutic shoeing systems on lameness and voluntary limb-load distribution in horses with chronic laminitis.
Animals: 10 horses with chronic laminitis.
Procedures: A clinical trial was conducted that used a concurrent control, crossover design to evaluate the relative effectiveness of a standard flat shoe, fullered egg-bar shoe, heart-bar shoe, and modified equine digital support system to alleviate chronic lameness in horses.
Objective: To evaluate the effect of prolonged water exposure on tissue mass and solutes of outer and inner layers of the stratum medium, sole, frog, and the stratum medium (SMZA) zona alba layer of horses' hooves. SPECIMEN POPULATION: 10 hooves from 10 horses without foot abnormalities.
Procedures: Hoof wall tissue specimens were obtained and immersed for 10 days in distilled deionized water.
Objective: To evaluate the clinical efficacy of topically administered glyceryl trinitrate (GTN) for inducing digital submural vasodilation in clinically normal horses.
Animals: 7 adult horses without foot abnormalities.
Procedures: A concurrent-control crossover design was used to determine whether topical application of GTN ointment for prevention or treatment of laminitis would result in a detectable increase in digital perfusion.
Objective: To determine whether a unique dihydropyridine (BAYTG 1000) would be beneficial in preventing laminitis in horses.
Animals: 16 clinically normal adult horses.
Procedure: 8 pairs of horses were used in a controlled double-blind study, using sex- and age-matched horses randomly assigned to treatment or control groups.