Publications by authors named "David M Gahan"
LSO:Ce Inorganic Scintillators Are Biocompatible With Neuronal and Circuit Function.
Front Synaptic Neurosci
September 2019
Optogenetics is widely used in neuroscience to control neural circuits. However, non-invasive methods for light delivery in brain are needed to avoid physical damage caused by current methods. One potential strategy could employ x-ray activation of radioluminescent particles (RPLs), enabling localized light generation within the brain.
View Article and Find Full Text PDFArticle Synopsis
- * The study successfully utilized the CRISPR-Cas9 system to target and induce specific mutations in the ndr2 gene in zebrafish embryos, leading to the expected cyclopic phenotypes.
- * Analysis revealed that most induced mutations resulted in small changes that disrupted normal gene function, enhancing the understanding of ndr2's role and demonstrating the effectiveness of CRISPR technology for targeted genetic studies.