Publications by authors named "David Lester"

Article Synopsis
  • The study aims to identify biochemical markers in individuals at risk of developing ALS or FTD due to the C9orf72 hexanucleotide repeat expansion (HRE).
  • Researchers compared levels of specific cerebrospinal fluid biomarkers in 48 asymptomatic C9orf72 HRE carriers, 39 controls, and various patient groups, finding increased levels of ubiquitin carboxyl-hydrolase isozyme L1 in carriers versus controls.
  • These elevated levels suggest early biochemical changes in C9orf72 HRE carriers that might be linked to disease mechanisms, enhancing understanding of disease progression and prevention strategies.
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: While there is substantial literature on gender and research productivity, bearing mixed results, no study is available for suicidology. The present investigation fills this gap and focuses on an influential elite. : Data are taken from the Web of Science (WoS).

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Background: Rewards can both validate and promote the stature of a researcher in their field. Research has been mixed on the role of gender as a predictor of receiving scholarly awards, but much of it lacks control for research excellence, and awards in interdisciplinary associations have been neglected. This study fills these gaps for suicidology.

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Research on the association between religiosity and personality with Arab participants is rare. The aim of the present study was to explore this association using a sample (N = 623) of college students from Sudan. They responded to the Arabic Scale of Intrinsic Religiosity and the Arabic Big-Five Personality Inventory.

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Background: The reduction of multiple psychiatric hospitalizations is an important clinical challenge in mental health care. In fact, psychiatric re-hospitalization negatively affects the quality of life and the life expectancy of patients with psychiatric disorders. For these reasons, identifying predictors of re-hospitalization is important for better managing psychiatric patients.

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The risks of indoor skydiving have not been extensively studied. Indoor skydiving facilities are often used for corporate events and parties and by relatively inexperienced participants who may not appreciate the risks involved. The abducted and externally rotated shoulder position, combined with nearby walls, tight spaces, and the strong airstream, has resulted in a pattern of shoulder dislocation injuries.

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Article Synopsis
  • The study aims to create guidelines for athletes returning to sports after total knee arthroplasty (TKA) and unicompartmental knee arthroplasty (UKA) by consolidating existing research findings.
  • A systematic review of studies from 2010 to 2020 showed that 34% to 100% of patients could return to sports within 12-13 weeks post-surgery, with UKA patients faring better and prior experience in the sport being a key factor.
  • Although low-impact sports like walking and swimming are recommended, the return to moderate-impact sports depends on individual cases, and high-impact sports are generally discouraged due to potential risks.
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Emotion dysregulation (ED) can be considered a psychopathological transdiagnostic dimension, the presence of which should be reliably screened in clinical settings. The aim of the current study was to validate the Italian version of the Emotion Dysregulation Scale-short (EDS-s), a brief self-report tool assessing emotion dysregulation, in a non-clinical sample of 1087 adults (768 women and 319 men). We also assessed its convergent validity with scales measuring binge eating and general psychopathology.

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Patients who have experienced emotional abuse and neglect often develop psychiatric disorders in adulthood. However, whether emotional abuse, neglect, and mentalization abilities relate to one another and the role of possible mediators of this relationship in psychiatric patients are still unknown. We evaluated the potential role of affective temperament as a mediator of the relationship between emotional abuse and neglect and mentalization.

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Mentalization is an important interpersonal ability, necessary for adaptive interpersonal relationships and emotion regulation. Deficits in mentalization have been associated with poor psychological outcomes and have been observed in patients with Borderline Personality Disorder. The Mentalization Questionnaire (MZQ) has been developed as self-report measure of mentalization deficit.

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