Clinical and spirometric variables are better predictors of COPD exacerbations than routine blood biomarkers.

Background: Understanding the risk factors for exacerbations of COPD may help provide a more personalised approach to exacerbation prevention.

Method: Observational, prospective, international, multicentre study aimed at identifying risk factors for exacerbations of COPD. Clinical variables, lung function and CAT scores were collected at baseline.

Acute interstitial pneumonia triggered by strenuous exercise.

Acute interstitial pneumonia (AIP) is a rare and severe form of idiopathic interstitial lung disease. Treatment is primarily supportive with supplemental oxygenation and mechanical ventilation. Prognosis is poor, but long-term survival is possible after recovery from AIP.

Association Between Routine Blood Biomarkers and Clinical Phenotypes and Exacerbations in Chronic Obstructive Pulmonary Disease.

Introduction: Chronic obstructive pulmonary disease (COPD) is associated with increased lung and systemic inflammation. We aimed to identify associations between easy-to-obtain blood biomarkers and the frequency and severity of exacerbations.

Methods: Cross-sectional, multicentre study performed in four centres in Spain, Italy, Bulgaria, and Slovenia.

Chitotriosidase Activity in Plasma and COPD Exacerbations.

Introduction: This study aimed to determine the association between plasma chitotriosidase activity and the clinical characteristics and exacerbation rate of COPD patients.

Methods: The study comprised 97 patients with COPD. Their clinical characteristics and a history of exacerbations in the last 12 months were noted.