Publications by authors named "David Kettl"
Article Synopsis
- * Population pharmacokinetic models indicated that body weight-based dosing for adolescents will give similar drug exposure as seen in adults.
- * The decision was supported by a long safety record of adalimumab and extrapolated effectiveness from adult studies, highlighting the relevance of this method for pediatric and rare disease drug approvals.
A pediatric kidney transplant recipient receiving tacrolimus for immunosuppression experienced symptoms consistent with idiopathic intracranial hypertension. The diagnosis of idiopathic intracranial hypertension and possible secondary causes of intracranial hypertension are reviewed in association with the patient's clinical course. Treatment options for the reversal of intracranial hypertension are summarized.
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