Publications by authors named "David Kapp"
Article Synopsis
- Chiari malformation 1 (CM1) is a condition where brain tissue herniates through the skull, typically noted when herniation measures over 3 or 5 mm.
- A case study featuring a 55-year-old male revealed he had a 4.87 mm herniation, along with symptoms like bilateral papilledema and monocular vision loss.
- Despite having CM1, his lumbar puncture showed normal intracranial pressure, raising questions about the typical association between papilledema and elevated pressure.
Background: The existence of protospacer adjacent motifs (PAMs) sequences in bacteriophage genome is critical for the recognition and function of the clustered regularly interspaced short palindromic repeats-Cas (CRISPR-Cas) machinery system. We further elucidate the significance of PAMs and their function, particularly as a part of transcriptional regulatory regions in T4 bacteriophages.
Methods: A scripting language was used to analyze a sequence of T4 phage genome, and a list of few selected PAMs.
Madelung's disease is a neglected metabolic disease characterised by generalised multiple fatty tissue deposits. A 64-year-old Caucasian woman presented with generalised weakness and symptomatic hypoglycaemia with altered mental status. Physical examination showed very distinct physical characteristics with multiple lumps distributed over the upper body.
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