Impact of Growth Hormone on Adult Bone Quality in Turner Syndrome: A HR-pQCT Study.

Women with Turner syndrome (TS) are known to be at risk of osteoporosis. While childhood growth hormone (GH) treatment is common in TS, the impact of this therapy on bone health has been poorly understood. The objective of this study was to determine the influence of childhood GH treatment on adult bone quality in women with TS.

Vitamin D concentrations among healthy children in Calgary, Alberta.

Objective: To examine the relationship between serum vitamin D concentrations, dietary intake and body mass index among healthy children living in Calgary, Alberta.

Methods: The present cross-sectional study included healthy children two to 13 years of age who presented to the Alberta Children's Hospital for elective surgery during a 12-month period. Data including the child's weight, height, age, sex, ethnicity, dietary intake, use of vitamin supplements, physical activity and time spent outdoors were collected.

Endocrine complications following pediatric bone marrow transplantation.

Pediatric bone marrow transplantation (BMT) for various diseases can lead to endocrine system dysfunction owing to preparative regimens involving chemotherapy and radiation therapy. We assessed the prevalence of post-BMT endocrine complications in children treated at the Alberta Children's Hospital (ACH) from 1991 to 2001. Time of onset of endocrine dysfunction, underlying disease processes, chemotherapy, radiation therapy and age at BMT were characterized.

Effect of type 1 diabetes on psychosocial maturation in young adults.

Purpose: Previous research suggests that having diabetes may complicate the passage from adolescence to adulthood. The aim of this study was to establish if young adults with Type 1 diabetes (T1DM) had delays in aspects of their psychosocial maturation compared with healthy controls (HC).

Methods: A cross-sectional study compared psychosocial maturation in individuals aged 18-25 years with T1DM to age-matched healthy controls.

Impact of growth hormone supplementation on adult height in turner syndrome: results of the Canadian randomized controlled trial.

Background: A randomized, controlled trial of GH supplementation to adult height in girls with short stature due to Turner syndrome was conducted in Canada. We report results in subjects who completed the protocol and subjects who participated in follow-up.

Methods: One hundred fifty-four girls with Turner syndrome, aged 7-13 yr, were randomly assigned to one of two groups: 1) GH by sc injection six times per week (0.