Publications by authors named "David K Fernandes"

Background: Engagement and partnership with consumers and communities throughout research processes produces high quality research meeting community needs and promoting translation of research into improved policy and practice. Partnership is critical in research involving Aboriginal and/or Torres Strait Islander people (First Nations Peoples) to ensure cultural safety. We present lessons from the design, implementation and progress of the National Health and Medical Research Council funded INtravenous iron polymaltose for First Nations Australian patients with high FERRitin levels on hemodialysis (INFERR) clinical trial.

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Article Synopsis
  • * A study compared the Abbott ARCHITECT i1000 (AA) and Ortho-Clinical Diagnostics Vitros 7600 (OCD) assays to understand the differences in ferritin measurements, which are critical for therapy decisions.
  • * Results showed that ferritin levels from the AA assay were consistently 36% to 44% higher than those from the OCD assay, indicating significant discrepancies that could impact clinical decision-making in CKD patients.
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Article Synopsis
  • The study investigates the effectiveness of intravenous iron treatment for First Nations Australians with end-stage kidney disease who have high ferritin levels and low transferrin saturation while undergoing haemodialysis.
  • It involves a randomized controlled trial with 576 participants, comparing those receiving monthly intravenous iron to a standard treatment group without iron therapy.
  • The main goal is to determine the impact of iron treatment on hospitalizations due to infections or overall mortality, alongside an economic analysis and other secondary outcomes.
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Background: Indigenous Australians are disproportionately affected by end stage kidney disease. Despite this, they face significant delays being assessed and waitlisted for kidney transplant.

Aims: To examine the kidney transplant waitlisting process in our region, to compare the workup process between Indigenous Australians and non-Indigenous patients, and identify major sources of delay.

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Aim: Acute postinfectious glomerulonephritis is common in indigenous communities in the Northern Territory, Australia. It is a major risk factor for the high prevalence of chronic kidney disease. We aimed to analyse the clinical presentation, pathological spectra, treatment and outcomes of biopsy-proven acute postinfectious glomerulonephritis in the Northern Territory.

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