Placental Size Is Associated Differentially With Postnatal Bone Size and Density.

We investigated relationships between placental size and offspring adolescent bone indices using a population-based, mother-offspring cohort. The Avon Longitudinal Study of Parents and Children (ALSPAC) recruited pregnant women from the southwest of England between 1991 and 1993. There were 12,942 singleton babies born at term who survived at least the first 12 months.

Childhood body mass index and adult pro-inflammatory and pro-thrombotic risk factors: data from the New Delhi birth cohort.

Objective: Weight gain and growth in early life may influence adult pro-inflammatory and pro-thrombotic cardiovascular risk factors.

Methods: Follow-up of a birth cohort in New Delhi, India, whose weight and height were measured every 6 months until age 21 years. Body mass index (BMI) at birth, during infancy (2 years), childhood (11 years) and adulthood (26-32 years) and BMI gain between these ages were analysed in 886 men and 640 women with respect to adult fibrinogen, high-sensitivity C-reactive protein (hsCRP) and plasminogen activator inhibitor-1 (PAI-1) concentrations.

Body mass index during childhood and adult body composition in men and women aged 56-70 y.

Background: The relation between the change in body mass index (BMI) through childhood and body composition in adult life is important because body composition is known to affect adult health.

Objective: The objective was to examine how the change in BMI throughout childhood is related to adult lean and fat mass.

Design: We examined how the change in BMI in childhood was related to adult body composition in 885 men and 1032 women born during 1934-1944, whose weights and heights during childhood were recorded serially.