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Publications by authors named "David Jonathan Gottlieb"

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Prophylactic antigen-specific T-cells targeting seven viral and fungal pathogens after allogeneic haemopoietic stem cell transplant.
David Jonathan Gottlieb Leighton Edward Clancy Barbara Withers Helen Marie McGuire Fabio Luciani

Clin Transl Immunology

March 2021

Objectives: Adoptive immunotherapy using donor-derived antigen-specific T-cells can prevent and treat infection after allogeneic haemopoietic stem cell transplant (HSCT).

Methods: We treated 11 patients with a prophylactic infusion of 2 × 10 cells per square metre donor-derived T-cells targeting seven infections (six viral and one fungal) following HSCT. Targeted pathogens were cytomegalovirus (CMV), Epstein-Barr virus (EBV), adenovirus, varicella zoster virus, influenza, BK virus (BKV) and .

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