Publications by authors named "David Jarmin"
Article Synopsis
- Researchers found that the beta-chemokine ESkine/CCL27 has two forms: a secreted version (ESkine) and a nuclear-targeted version (PESKY) that lacks a signal peptide.
- * The study identified that PESKY's movement into the nucleus depends on specific C-terminal residues, which are also present in ESkine, suggesting both can enter the nucleus through a similar mechanism.
- * Overexpression of PESKY in cells led to significant changes in the actin cytoskeleton and increased cell migration, indicating a possible new role for these chemokines in cellular movement and structure.*
