Publications by authors named "David J Rosenthal"
Antibiotics (Basel)
October 2014
Article Synopsis
- CXCL10 is a small, antimicrobial chemokine induced by IFN-γ that attracts immune cells and binds T cells.
- It effectively inhibits the growth of certain bacteria and fungi, including Escherichia coli and Staphylococcus aureus, but doesn't affect others, suggesting a selective antimicrobial action with unknown mechanisms.
- The structural composition of CXCL10, characterized by positively charged amino acids and specific secondary structures, likely contributes to its antimicrobial properties and potential role in enhancing immune responses on the skin and in the oral cavity.
