Synopsis of recent research by authors named "David J Kroll"
- David J Kroll's research primarily focuses on the bioactive properties of natural compounds derived from fungi and plants, particularly in the context of cancer chemoprevention and treatment.
- Notable findings include the identification of silibinin and its methylation products as promising epigenetic modulators against prostate carcinoma, alongside the discovery of novel compounds from various filamentous fungi with significant cytotoxic and antibacterial activities.
- Kroll's work employs advanced techniques like bioactivity-directed fractionation, NMR spectroscopy, and the hollow fiber assay to isolate and evaluate the therapeutic potential of these natural products, which could lead to new anticancer agents.
