The role of clopidogrel in the management of ischemic heart disease.

Purpose Of Review: Placebo-controlled randomized trials have demonstrated the efficacy of clopidogrel in combination with aspirin across a broad range of clinical presentations. Recent trials have addressed several remaining issues regarding clopidogrel therapy.

Recent Findings: Three randomized trials examined the role of platelet function testing (PFT) in clopidogrel-treated patients.

Coffee: good, bad, or just fun? A critical review of coffee's effects on liver enzymes.

Coffee consumption is a regular part of daily life throughout the world. Research into the effects of coffee on human health is ongoing, but a recent study suggests that coffee and caffeine consumption can reduce the risk of elevated alanine aminotransferase activity in individuals at high risk for liver disease. This review will analyze the results of that study in light of the current literature.