Cell-free production of a functional oligomeric form of a major outer-membrane protein (MOMP) for vaccine development.

Chlamydia is a prevalent sexually transmitted disease that infects more than 100 million people worldwide. Although most individuals infected with are initially asymptomatic, symptoms can arise if left undiagnosed. Long-term infection can result in debilitating conditions such as pelvic inflammatory disease, infertility, and blindness.

The role of clopidogrel in the management of ischemic heart disease.

Purpose Of Review: Placebo-controlled randomized trials have demonstrated the efficacy of clopidogrel in combination with aspirin across a broad range of clinical presentations. Recent trials have addressed several remaining issues regarding clopidogrel therapy.

Recent Findings: Three randomized trials examined the role of platelet function testing (PFT) in clopidogrel-treated patients.

Long-term clinical outcomes of real-world experience using sirolimus-eluting stents in saphenous vein graft disease.

Objective: To evaluate the long-term clinical outcomes of patients undergoing percutaneous coronary intervention for saphenous vein graft (SVG) disease. Specifically, we compared clinical endpoints of patients who received sirolimus-eluting stents (SES) versus bare-metal stents (BMS) for SVG disease.

Background: A recent small randomized-controlled trial (RCT) reported increased mortality with the use of SES in SVG disease.

The hidden curriculum: medical students' changing opinions toward the pharmaceutical industry.

Background: Authorities suggest academic medical centers eliminate conflicts of interest. The authors evaluated medical students' opinions and knowledge of the pharmaceutical industry.

Method: An anonymous 20-item questionnaire was administered to medical students from four different medical schools; 15 items addressed opinions, and five items were free-response knowledge questions.

Coffee: good, bad, or just fun? A critical review of coffee's effects on liver enzymes.

Coffee consumption is a regular part of daily life throughout the world. Research into the effects of coffee on human health is ongoing, but a recent study suggests that coffee and caffeine consumption can reduce the risk of elevated alanine aminotransferase activity in individuals at high risk for liver disease. This review will analyze the results of that study in light of the current literature.