Survey of genomic and physiological characteristics for survival in lymphoma: The NCI genomic data portal.

Lymphoma represents a myriad collection of neoplasms that impact lymphocytes. This cancer often involves disrupted cytokine, immune surveillance, and gene regulatory signaling, sometimes with expression of Epstein Barr Virus (EBV). We explored mutation patterns for People experiencing Lymphoma (PeL) in the National Cancer Institute (NCI) Genomic Data Commons (GDC), which contains detailed, deidentified genomic data on 86,046 people who have/had cancer with 2,730,388 distinctive mutations in 21,773 genes.

The competition of ecological resonances in the quantum metabolic model of cancer: Potential energetic interventions.

Cancer (a) represents an atavistic reversion to attempted asexual reproduction; (b) metastasizes to absorber "soil" tissues based upon temporal, ontogenetic commonalities; (c) cycles/precesses with competitive immunological surveillance and self-competition within the ecological environment of the body; and (d) is potentially manageable via quantum information qubit phase transitions and universal principles of thermodynamic hysteresis and resonant driving forces . We use retro-recognition of evidence-based cancer anomalies to make these arguments, which in sum position cancer as an ecological quantum information problem. The findings reposition the quantum metabolic model of cancer and presents a research approach aimed at applied treatments: Tertiary Lymphoid Structure ecological competition with cellular transmembrane quantum energy boosting using VDAC and other voltage gated ion channels.

Allostatic Load, Mobility Disability, and Viral Effects in Cancer: A Structural Equation Model.

A growing number of cancers have been linked to specific oncogenic viruses and physiological stress. Recently, two separate studies linked mobility limitations to allostatic load and four major cancer types. The objective of this study was to determine if cancer occurrence regresses on three latent domains of Allostatic Load, Level of Physical Functioning (i.

Disability and health outcomes in geospatial analyses of Southeastern U.S. county health data.

Background: People with disabilities tend to be at risk for secondary conditions. There is a need for comprehensive disability and health databases, including geographic information systems to evaluate trends in health, functioning, and employment.

Objective: We evaluated county levels in morbidity and mortality across the Southeastern United States using spatial regression, examining 2015 trends in accordance with Healthy People 2020 objectives.

Biomarkers of chondriome topology and function: implications for the extension of healthy aging.

Multiple theories of aging (e.g., free radical, error catastrophe, mitochondrial) are complementary but fail to provide adequate models that comprehensively predict lifelong aging processes and that are valid across species.

Heart age differentials and general cardiovascular risk profiles for persons with varying disabilities: NHANES 2001-2010.

Background: Persons with disabilities are at risk for secondary conditions, including allostatic load contributing to cardiovascular disease. The General Cardiovascular Risk Profile (GCRP) estimates cardiovascular disease risk for individuals. The GCRP variables are present in the National Health and Nutrition Examination Survey (NHANES) for the Healthy People 2010 decade.

Cross-sectional changes in patterns of allostatic load among persons with varying disabilities, NHANES: 2001-2010.

Background: Allostatic Load (AL) is a measure of physiological stress that correlates with morbidity and mortality.

Objective: The purpose of this study was to evaluate patterns of AL among persons with each of eight categories of disability versus persons with no disabilities over the 10-year Healthy People 2010 examination period.

Methods: The study examined measures of AL from the 2001-2010 National Health and Nutrition Examination Survey (NHANES).

Attitudes & effectiveness of professional programs for primary prevention of violence: exploratory validation of the PREVENT primary prevention of violence self-assessment.

The PREVENT (Preventing Violence through Education, Networking, and Technical Assistance) project trained violence practitioners across the USA in Primary Prevention of Violence techniques (PPV). The purpose of this study is to describe the development and psychometric properties of the subscales of the PREVENT PPV Self Assessment. Of 800 participants, 585 responded (73.

Concurrent validation of CHIRP, a new instrument for measuring healthcare student attitudes towards interdisciplinary teamwork.

Positive attitudes towards teamwork among health care professionals are critical to patient safety. The purpose of this study is to describe the development and concurrent validation of a new instrument to measure attitudes towards healthcare teamwork that is generalizable across various populations of healthcare students. The Collaborative Healthcare Interdisciplinary Planning (CHIRP) scale was validated against the Readiness for Inter-Professional Learning Scale (RIPLS).

Exploratory validation of the Fruit and Vegetable Neophobia Instrument among third- to fifth-grade students.

Children's unwillingness to try new foods, or food neophobia, may impact dietary behaviors. As part of an effort to evaluate Farm to School programs, the Fruit and Vegetable Neophobia Instrument (FVNI) was developed to measure student attitudes toward new fruits and vegetables. A self-administered, paper/pencil, 18-item questionnaire, the FVNI was adapted from the Food Neophobia Scale.

Effect of a geriatric curriculum on emergency medicine resident attitudes, knowledge, and decision-making.

Objectives: Despite an increasing number of elderly emergency department (ED) patients, emergency medicine (EM) residency training lacks geriatric-specific curricula. The objective was to determine if a 1-year geriatric curriculum, designed for residents, would affect residents' attitudes, knowledge, and decision-making for older patients seen in the ED.

Methods: The authors created a geriatric curriculum for EM residents composed of six lectures on the following topics: trauma, abdominal pain, transitions of care, medication management, iatrogenic injuries, and confusional states.

Creating a multi-institutional family medicine clerkship examination: lessons learned.

Background And Objectives: Multiple choice examinations assess learners' attainment of medical knowledge. Developing multiple choice examinations that discriminate among learners is difficult and time-consuming. Many institutions avoid this effort by using the National Board of Medical Examiners (NBME) subject examinations, which can also provide comparisons to a national norm.

Teamwork training with nursing and medical students: does the method matter? Results of an interinstitutional, interdisciplinary collaboration.

Objectives: The authors conducted a randomised controlled trial of four pedagogical methods commonly used to deliver teamwork training and measured the effects of each method on the acquisition of student teamwork knowledge, skills, and attitudes.

Methods: The authors recruited 203 senior nursing students and 235 fourth-year medical students (total N = 438) from two major universities for a 1-day interdisciplinary teamwork training course. All participants received a didactic lecture and then were randomly assigned to one of four educational methods didactic (control), audience response didactic, role play and human patient simulation.

Griev_Ing: death notification skills and applications for fourth-year medical students.

Background And Purpose: Our study examined whether GRIEV_ING improved death notification skills of medical students, whether pretesting with simulated survivors primed learners and improved results of the intervention, and whether feedback on the simulated encounter improved student performance.

Methods: GRIEV_ING training was given to 138 fourth-year medical students divided into three groups: exposure to simulated survivor (SS) with written feedback, exposure to SS but no feedback, and no exposure to SS before the training. Students were tested on self-confidence before and after the intervention and were rated by SSs on interpersonal communication and death notification skills.

Utility of the AAMC's Graduation Questionnaire to study behavioral and social sciences domains in undergraduate medical education.

Purpose: The Institute of Medicine (IOM) report on social and behavioral sciences (SBS) indicated that 50% of morbidity and mortality in the United States is associated with SBS factors, which the report also found were inadequately taught in medical school. A multischool collaborative explored whether the Association of American Medical Colleges Graduation Questionnaire (GQ) could be used to study changes in the six SBS domains identified in the IOM report.

Method: A content analysis conducted with the GQ identified 30 SBS variables, which were narrowed to 24 using a modified Delphi approach.

Selection, training and retention of an armed private security department.

To arm or not to arm security officers? One hospital which has opted for arming its officers is Cook Children's Healthcare System, Fort Worth, TX, an integrated pediatric healthcare facility with over 4000 employees. Because of its location in a major metropolitan area and based on several factors including demographics, exterior risk assessments and crime statistics, the hospital's Administration and its Risk Manager supported the decision to operate as an armed security force, according to the author. In this article he shares its current program and presents some thoughts and ideas that may benefit others who are considering this important step.

Progress along developmental tracks for electronic health records implementation in the United States.

The development and implementation of electronic health records (EHR) have occurred slowly in the United States. To date, these approaches have, for the most part, followed four developmental tracks: (a) Enhancement of immunization registries and linkage with other health records to produce Child Health Profiles (CHP), (b) Regional Health Information Organization (RHIO) demonstration projects to link together patient medical records, (c) Insurance company projects linked to ICD-9 codes and patient records for cost-benefit assessments, and (d) Consortia of EHR developers collaborating to model systems requirements and standards for data linkage. Until recently, these separate efforts have been conducted in the very silos that they had intended to eliminate, and there is still considerable debate concerning health professionals access to as well as commitment to using EHR if these systems are provided.

Increasing interest in child and adolescent psychiatry in the third-year clerkship: results from a post-clerkship survey.

Objective: The authors aimed to determine whether a structured clinical experience in child and adolescent psychiatry (CAP) during the third-year psychiatry clerkship would impact interest in pursuing careers in psychiatry and CAP.

Methods: The authors constructed and administered a postrotation survey, the Child and Adolescent Psychiatry Experiences Questionnaire (CAPE-Q), to evaluate clinical experiences and career interest in psychiatry and CAP both before and after a clerkship in psychiatry. The value of specific aspects of the clerkship to students' career decisions was also assessed.

Risk behaviors for varying categories of disability in NELS:88.

A large body of research shows that youth with disabilities, who comprise about 13% of the country's school-aged population, report comparable to higher incidence rates of alcohol, tobacco, and other drug (ATOD) use than their peers. Furthermore, youth with disabilities who reported ATOD use or who engaged in binge drinking had significantly more negative educational outcomes and engaged in sexual activity at a younger age than nonusers. This study describes risk factors for substance use, personal characteristics, aspects of the attitudinal environment, and educational, employment, and social outcomes among youth across 6 categories of disability.

Relationship of substance use by students with disabilities to long-term educational, employment, and social outcomes.

The study is based on data from the National Education Longitudinal Study of 1988-2000 (NELS: 88). The results indicate that adolescents with disabilities who used either cigarettes or marijuana or who engaged in binge drinking had significantly higher dropout rates, lower high school graduation status, lower college attendance, and lower high school grade point averages, and fewer earned core credit units in English, science, and mathematics than nonusers. In addition, adolescents with disabilities who used either cigarettes, alcohol, or drugs were significantly more likely to engage in sexual activity at a younger age.