Publications by authors named "David Hickok"
Article Synopsis
- * Recent advancements in genome sequencing and assembly techniques allow for the creation of high-quality reference genomes, which can now include various genetic variations through pan-genome development.
- * By analyzing these pan-genomes, researchers aim to pinpoint the genetic factors behind desirable traits, paving the way for more efficient breeding and the production of innovative cultivars with enhanced qualities.
Heterogeneous prostatic carcinoma-associated fibroblasts (CAF) contribute to tumor progression and resistance to androgen signaling deprivation therapy (ADT). CAF subjected to extended passaging, compared to low passage CAF, were found to lose tumor expansion potential and heterogeneity. Cell surface endoglin (CD105), known to be expressed on proliferative endothelia and mesenchymal stem cells, was diminished in high passage CAF.
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