Objective: High-flow nasal cannula use in the PICU continues to increase; however, a protocol for weaning patients has yet to be published. This study aimed to create an efficient and safe protocol for weaning high-flow nasal cannula.
Design: A Respiratory Assessment Score was created using two validated scoring systems.
Background: Children with severe bronchospasm requiring mechanical ventilation may become refractory to conventional therapy. In these critically ill patients, isoflurane is an inhaled anesthetic agent available in some centers to treat bronchospasm. We hypothesized that isoflurane is safe and would lead to improved gas exchange in children with life-threatening bronchospasm refractory to conventional therapy.
View Article and Find Full Text PDFPediatr Crit Care Med
July 2009
Objective: To determine which flow setting most accurately detects the lower inflection point (Pflex) using an automated constant flow method and varying endotracheal tube (ETT) sizes with and without an airleak in a pediatric lung model.
Design: Interventional laboratory study.
Setting: Children's hospital research center.
Objective: To identify the effect of perflubron on gas exchange and lung mechanics during high frequency oscillatory ventilation in an animal model.
Design: Prospective randomized animal trial.
Subjects: Eighteen Yorkshire swine.