The effect of maternal oxygen administration on fetal pulse oximetry during labor in fetuses with nonreassuring fetal heart rate patterns.

Objective: Using fetal pulse oximetry, we sought to quantify the impact of maternal oxygen administration in the management of nonreassuring fetal heart rate patterns.

Study Design: In fetuses with specified abnormal nonreassuring fetal heart rate patterns, oxygen was administered to the mother, and fetal oxygenation was monitored with fetal pulse oximetry. After the fetal oxygen saturation on room air was recorded as a baseline, oxygen was administered to the mother for 30 minutes at 40% fraction of inspired oxygen and then 30 minutes at 100% of inspired oxygen.

Dose response of RU486 in a novel rabbit model of noninfectious preterm birth: comparative efficacy of 3 routes of administration.

Objective: The purpose of this study was to examine whether the pregnant rabbit model can be used as a viable model for the study of non-infection-mediated preterm birth.

Study Design: Timed pregnant New Zealand rabbits were injected with a single dose of RU486 on day 22 of gestation. Three doses (50 mg, 75 mg, and 100 mg) were administered intramuscularly, intraperitoneally, or subcutaneously.

Fetal pulse oximetry: correlation between oxygen desaturation, duration, and frequency and neonatal outcomes.

Objective: The purpose of this study was to identify the threshold of fetal arterial oxyhemoglobin saturation that predicts neonatal acidosis and adverse outcomes.

Study Design: Fetal oxygen saturation data from a published randomized controlled trial of fetal pulse oximetry were evaluated in relation to the number and duration of low fetal oxygen saturation episodes and neonatal outcomes. Fetal oxygen saturation episodes (epochs) of at least 10-second duration were categorized into the following groups: (1).