Publications by authors named "David Garnica Agudelo"
Article Synopsis
- Genetic generalized epilepsy (GGE) is a brain disorder characterized by widespread connectivity issues, which can be studied using simultaneous EEG and fMRI, but there are challenges due to MRI-related artifacts affecting the EEG data.
- This study explored the effects of these artifacts on group comparisons of EEG power and functional connectivity between GGE patients and healthy controls, finding that while some power differences were reduced in significance, measures of functional connectivity (ImCoh) remained consistent across conditions.
- Notably, increased functional connectivity was observed in GGE patients, particularly from the thalamus to the precuneus cortex, suggesting that using ImCoh for EEG analysis within the MRI is valid and that group differences can be effectively maintained despite the measurement conditions
Objective: Presurgical high-density electric source imaging (hdESI) of interictal epileptic discharges (IEDs) is only used by few epilepsy centers. One obstacle is the time-consuming workflow both for recording as well as for visual review. Therefore, we analyzed the effect of (a) an automated IED detection and (b) the number of IEDs on the accuracy of hdESI and time-effectiveness.
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