Publications by authors named "David E Wilkins"
Purpose: To investigate the dependence of the alpha/beta ratio determined from in vitro survival curves on the dose ranges.
Methods: Detailed clonogenic cell survival experiments were used to determine the least squares estimators for the linear quadratic model for different dose ranges. The cell lines used were CHO AA8, a Chinese hamster fibroblast cell line; U-373 MG, a human glioblastoma cell line; and CP3 and DU-145, two human prostate carcinoma cell lines.