Publications by authors named "David E OʼNeill"
Case: A 56-year-old woman with metastatic melanoma and femoral lesions with impending pathologic fracture was indicated for intramedullary brachytherapy (IMBT) and intramedullary nail.
Conclusions: IMBT + intramedullary nail is a new technique for the treatment of long bone metastases. IMBT maximizes radiation to the tumor and minimizes radiation to surrounding tissues.
To compare the stability of screw fixation with that of plate fixation for symphyseal injuries in a vertically unstable pelvic injury (AO/Tile 61-C1) associated with complete disruption of the sacroiliac joint and the pubic symphysis. Eight fourth-generation composite pelvis models with sacroiliac and pubic symphyseal disruption (Sawbones, Vashon Island, WA) underwent biomechanical testing simulating static single-leg stance. Four were fixed anteriorly with a symphyseal screw, and 4 with a symphyseal plate.
View Article and Find Full Text PDFObjectives: To evaluate the need for reoperation of geriatric intertrochanteric hip fractures treated with 10-mm cephalomedullary nails versus those treated with nails larger than 10 mm.
Design: Retrospective review at a single institution.
Setting: Level I trauma center.
Article Synopsis
- The study aimed to evaluate the effectiveness of acute-phase markers like white blood cell (WBC) count, erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP) in diagnosing upper extremity infections that require surgery.
- A retrospective analysis over 12 years identified 61 patients, revealing that CRP was the most sensitive indicator for detecting culture-positive infections, with 90% of patients showing abnormal CRP levels.
- In contrast, only 54% and 67% of patients had abnormal WBC counts and ESR levels, respectively, suggesting that these tests should be interpreted with caution since they can appear normal even when an infection is present.
Objective: To characterize the presentation and outcomes of calcaneal avulsion fractures.
Design: Case series.
Setting: Two ACS Level I trauma centers.
Objectives: To determine whether sarcopenia is an independent predictor of mortality in geriatric acetabular fractures.
Design: Retrospective cohort.
Setting: American College of Surgeons Level I trauma center.
Objective: To define the pathoanatomy of the tongue-type calcaneus fracture and assess the appropriateness of percutaneous techniques in addressing all planes of deformity in this injury.
Design: Retrospective cohort.
Setting: ACS Level I trauma center.
Background: Acquired Jeune's syndrome is a severe iatrogenic deformity of the thoracic wall following a premature and aggressive open pectus excavatum repair. We report herein our technique and experience with this rare condition.
Methods: From 1996 to 2011, nineteen patients with acquired Jeune's syndrome were retrospectively identified in a tertiary referral center.
Heat shock protein 72 (Hsp70) is constitutively expressed in rat hindlimb muscles, reportedly in proportion to their content of type I myosin heavy chain. This distribution pattern has been suggested to result from the higher recruitment and activity of such muscles and/or a specific relationship between myosin phenotype and Hsp70 content. To differentiate between these possibilities, the fiber-specific distribution of Hsp70 was examined in male Sprague-Dawley rat plantaris under control conditions, following a fast-to-slow phenotypic shift in response to surgically induced overload (O) and in response to O when the phenotypic shift was prevented by 3,5,3'-triiodo-dl-thyronine administration.
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