Influence of preoperative magnetic resonance imaging on the surgical management of breast cancer patients.

Background: Magnetic resonance imaging (MRI) is gaining popularity in the preoperative management of breast cancer patients. However, the role of this modality remains controversial. We aimed to study the impact of preoperative MRI (pMRI) on the surgical management of breast cancer patients.

Bupropion, smoking cessation, and health-related quality of life following an acute myocardial infarction.

Background: The use of bupropion, a smoking cessation aid, has been associated with improved health-related quality of life (HRQOL) in the general population of smokers; but, its effect on HRQOL in post-myocardial infarction (MI) patients remains unknown.

Objectives: To examine the effect of bupropion on HRQOL in post-MI patients who are attempting to quit smoking.

Methods: To accomplish this objective, we used data from a randomized, double-blind, placebo-controlled trial in 392 hospitalized post-MI patients.

Efficacy of Methylphenidate in ADHD Children across the Normal and the Gifted Intellectual Spectrum.

Objective: This study evaluates whether attention-deficit/hyperactivity disorder (ADHD) children with a borderline intelligence quotient (IQ) (70≤FSIQ<80), normal IQ (80≤FSIQ<120) and high IQ (FSIQ≥120) respond differently to psychostimulant treatment.

Method: 502 children, aged 6 to 12 years, with an IQ range from 70 to 150 participated in a two-week, double-blind, placebo-controlled, crossover methylphenidate (MPH) trial.

Results: In addition to differences in socioeconomic background and parental education, higher IQ children were found to present with less severe symptoms.