Publications by authors named "David Deutscher"
Article Synopsis
- The Victorian Pancreas Cancer summit 2017 analyzed cancer care data from 2011-2015 to identify differences in treatment and outcomes for patients with pancreatic cancer in Victoria.
- Findings revealed that 82% of patients had ductal adenocarcinoma, with a one-year overall survival rate of only 30%, indicating significant challenges in managing the disease.
- Despite the importance of surgery, many patients either did not receive systemic therapy or did not undergo necessary surgical procedures, highlighting the need for improved treatment strategies for pancreatic cancer.
Objective: To compare bursting strength, construction time, and anastomotic dimensions of 4 jejunoileal anastomotic techniques.
Study Design: Experimental ex vivo study.
Animals: Adult horses (n = 12).
Background: When analyzing complex biological systems, a major objective is localization of function - assessing how much each element contributes to the execution of specific tasks. To establish causal relationships, knockout and perturbation studies are commonly executed. The vast majority of studies perturb a single element at a time, yet one may hypothesize that in non-trivial biological systems single-perturbations will fail to reveal the functional organization of the system, owing to interactions and redundancies.
View Article and Find Full Text PDFGenetic robustness characterizes the constancy of the phenotype in face of heritable perturbations. Previous investigations have used comprehensive single and double gene knockouts to study gene essentiality and pairwise gene interactions in the yeast Saccharomyces cerevisiae. Here we conduct an in silico multiple knockout investigation of a flux balance analysis model of the yeast's metabolic network.
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