Publications by authors named "David Courtois"

Article Synopsis
  • Infectious Bronchitis virus (IBV) is causing major economic issues for the chicken industry, even with the use of live vaccines, and there are concerns that these vaccines may lead to new virus strains.
  • A study was conducted where SPF chickens were either vaccinated with a different live vaccine or left unvaccinated and then exposed to a challenge IBV virus, leading to distinct genetic changes in the virus populations.
  • The unvaccinated birds showed rapid evolution with more genetic variants, while the vaccinated group had fewer changes, highlighting different evolutionary paths for the virus in these two settings.
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Infectious bursal disease virus (IBDV, family Birnaviridae) is a bi-segmented double-stranded RNA virus for which two serotypes are described. Serotype 1 replicates in the bursa of Fabricius and causes an immunosuppressive and potentially fatal disease in young chickens. Serotype 2 is apathogenic in poultry species.

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Highly pathogenic (HP) H5N1 avian influenza (AI) is enzootic in several countries of Asia and Africa and constitutes a major threat, at the world level, for both animal and public health. Ducks play an important role in the epidemiology of AI, including HP H5N1 AI. Although vaccination can be a useful tool to control AI, duck vaccination has not proved very efficient in the field, indicating a need to develop new vaccines and a challenge model to evaluate the protection for duck species.

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