The cross-cultural big two: A culturally decentered theoretical and measurement model for personality traits.

A "big two" model has shown stronger cross-cultural replicability and links to theory than other contemporary models of personality trait structure. However, its theoretical and measurement models require better specification. We address this to create an initial English-language version of the Cross-Cultural Big Two Inventory with an empirically informed and culturally decentered approach, meaning that input from global contexts is used from the outset, without prioritizing Western perspectives.

The person-environment fit of immigrants to the United States: A registered report.

There are notable parallels between processes leading to person-environment fit (PE-fit) and processes of selection and acculturation among U.S. immigrants.

Scaling a common assessment of associative ability: Development and validation of a multiple-choice compound remote associates task.

The assessment of creativity as an individual difference has historically focused on divergent thinking, which is increasingly viewed as involving the associative processes that are also understood to be a key component of creative potential. Research on associative processes has proliferated in many sub-fields, often using Compound Remote Associates (CRA) tasks with an open response format and relatively small participant samples. In the present work, we introduce a new format that is more amenable to large-scale data collection in survey designs, and present evidence for the reliability and validity of CRA measures in general using multiple large samples.

Development of a Public-Domain Measure of Two-Dimensional Rotation Ability and Preliminary Evidence for Discriminant Validity among Occupations.

Despite their known influence in science, technology, engineering, and mathematics (STEM) fields, spatial abilities remain an underassessed aspect of cognition, particularly in educational settings. One explanation could be a lack of affordable, valid instruments for measuring various aspects of spatial ability. We evaluate the validity of a set of public-domain, algorithmically generated two-dimensional rotation items using a sample from the Synthetic Aperture Personality Assessment (SAPA) Project ( = 1,020,195).

Deep lexical hypothesis: Identifying personality structure in natural language.

Recent advances in natural language processing (NLP) have produced general models that can perform complex tasks such as summarizing long passages and translating across languages. Here, we introduce a method to extract adjective similarities from language models as done with survey-based ratings in traditional psycholexical studies but using millions of times more text in a natural setting. The correlational structure produced through this method is highly similar to that of self- and other-ratings of 435 English terms reported by Saucier and Goldberg (1996a).

Establishing analytical validity of BeadChip array genotype data by comparison to whole-genome sequence and standard benchmark datasets.

Background: Clinical use of genotype data requires high positive predictive value (PPV) and thorough understanding of the genotyping platform characteristics. BeadChip arrays, such as the Global Screening Array (GSA), potentially offer a high-throughput, low-cost clinical screen for known variants. We hypothesize that quality assessment and comparison to whole-genome sequence and benchmark data establish the analytical validity of GSA genotyping.

Psychosocial factors associated with preventive pediatric care during the COVID-19 pandemic.

Background: Identifying the factors that predict non-adherence to recommended preventive pediatric care is necessary for the development of successful interventions to improve compliance.

Purpose: Given the substantial decline in well-child visits and influenza vaccinations, we sought to examine sociodemographic (i.e.

Lung Pericytes in Pulmonary Vascular Physiology and Pathophysiology.

Pericytes are mesenchymal-derived mural cells localized within the basement membrane of pulmonary and systemic capillaries. Besides structural support, pericytes control vascular tone, produce extracellular matrix components, and cytokines responsible for promoting vascular homeostasis and angiogenesis. However, pericytes can also contribute to vascular pathology through the production of pro-inflammatory and pro-fibrotic cytokines, differentiation into myofibroblast-like cells, destruction of the extracellular matrix, and dissociation from the vessel wall.

Novel and Variants Are Implicated in the Pathogenesis of Pulmonary Arterial Hypertension.

Pulmonary arterial hypertension (PAH) is a rare disease characterized by pulmonary vascular remodeling and right heart failure. Specific genetic variants increase the incidence of PAH in carriers with a family history of PAH, those who suffer from certain medical conditions, and even those with no apparent risk factors. Inflammation and immune dysregulation are related to vascular remodeling in PAH, but whether genetic susceptibility modifies the PAH immune response is unclear.

Why Has Personality Psychology Played an Outsized Role in the Credibility Revolution?

Personality is not the most popular subfield of psychology. But, in one way or another, personality psychologists have played an outsized role in the ongoing "credibility revolution" in psychology. Not only have individual personality psychologists taken on visible roles in the movement, but our field's practices and norms have now become models for other fields to emulate (or, for those who share Baumeister's (2016, https://doi.

Personality Predictors of Emergency Department Post-Discharge Outcomes.

Personality traits are important predictors of health behaviors, healthcare utilization, and health outcomes. However, we know little about the role of personality traits for emergency department outcomes. The present study used data from 200 patients (effective Ns range from 84 to 191), who were being discharged from the emergency department at an urban hospital, to investigate whether the Big Five personality traits were associated with post-discharge outcomes (i.

The distinction between symptoms and traits in the Hierarchical Taxonomy of Psychopathology (HiTOP).

The Hierarchical Taxonomy of Psychopathology (HiTOP) is an empirically and quantitatively derived dimensional classification system designed to describe the features of psychopathology and, ultimately, to replace categorical nosologies. Among the constructs that HiTOP organizes are "symptom components" and "maladaptive traits," but past HiTOP publications have not fully explicated the distinction between symptoms and traits. We propose working definitions of symptoms and traits and explore challenges, exceptions, and remaining questions.

From 2D to 3D: Promising Advances in Imaging Lung Structure.

The delicate structure of murine lungs poses many challenges for acquiring high-quality images that truly represent the living lung. Here, we describe several optimized procedures for obtaining and imaging murine lung tissue. Compared to traditional paraffin cross-section and optimal cutting temperature (OCT), agarose-inflated vibratome sections (aka precision-cut lung slices), combines comparable structural preservation with experimental flexibility.

Exposure to Gestational Diabetes Enriches Immune-Related Pathways in the Transcriptome and Methylome of Human Amniocytes.

Context: Gestational diabetes (GDM) has profound effects on the intrauterine metabolic milieu and is linked to obesity and diabetes in offspring, but the mechanisms driving these effects remain largely unknown. Alterations in DNA methylation and gene expression in amniocytes exposed to GDM in utero represent a potential mechanism leading to metabolic dysfunction later in life.

Objective: To profile changes in genome-wide DNA methylation and expression in human amniocytes exposed to GDM.

Mural Cell SDF1 Signaling Is Associated with the Pathogenesis of Pulmonary Arterial Hypertension.

Pulmonary artery smooth muscle cells (PASMCs) and pericytes are NG2 mural cells that provide structural support to pulmonary arteries and capillaries. In pulmonary arterial hypertension (PAH), both mural cell types contribute to PA muscularization, but whether similar mechanisms are responsible for their behavior is unknown. RNA-seq was used to compare the gene profile of pericytes and PASMCs from PAH and healthy lungs.

Diagnosis and Management of Pulmonary Hypertension in the Modern Era: Insights from the 6th World Symposium.

The past 20 years have seen major advances in the diagnosis and management of pulmonary hypertension, a disease associated with significant morbidity and mortality. The 6th World Symposium in Pulmonary Hypertension (WSPH) took place in February 2018 and attempted to consolidate the current knowledge in the field into practical recommendations to help prioritize an action plan to improve patient outcomes and identify future research directions. In this review, we will summarize the highlights of the 6th WSPH proceedings, including revisions to the hemodynamic definitions and classification of the various types of pulmonary hypertension, genetic advances, approaches to risk stratification, and updated treatment algorithms.

Who Are the Scrooges? Personality Predictors of Holiday Spending.

The sharp increase in consumption over the holiday season has important economic implications, yet the psychology underlying this phenomenon has received limited attention. Here, we evaluate the role of individual differences in holiday spending patterns. Using 2 million transactions across 2,133 individuals, we investigate the relationship between the Big 5 personality traits on spending at Christmas.

Does recall period matter? Comparing PROMIS physical function with no recall, 24-hr recall, and 7-day recall.

Purpose: To evaluate the influence of recall periods on the assessment of physical function, we compared, in cancer and general population samples, the standard administration of PROMIS Physical Function items without a recall period to administrations with 24-hour and 7-day recall periods.

Methods: We administered 31 items from the PROMIS Physical Function v2.0 item bank to 2400 respondents (n = 1001 with cancer; n = 1399 from the general population).