Impact of sub and supra-threshold adaptation currents in networks of spiking neurons.

Neuronal adaptation is the intrinsic capacity of the brain to change, by various mechanisms, its dynamical responses as a function of the context. Such a phenomena, widely observed in vivo and in vitro, is known to be crucial in homeostatic regulation of the activity and gain control. The effects of adaptation have already been studied at the single-cell level, resulting from either voltage or calcium gated channels both activated by the spiking activity and modulating the dynamical responses of the neurons.

Working memory dynamics and spontaneous activity in a flip-flop oscillations network model with a Milnor attractor.

Many cognitive tasks require the ability to maintain and manipulate simultaneously several chunks of information. Numerous neurobiological observations have reported that this ability, known as the working memory, is associated with both a slow oscillation (leading to the up and down states) and the presence of the theta rhythm. Furthermore, during resting state, the spontaneous activity of the cortex exhibits exquisite spatiotemporal patterns sharing similar features with the ones observed during specific memory tasks.