Publications by authors named "David Carlos"

Purpose: Recurrent diffuse-type tenosynovial giant cell tumor: Clinical presentation, Diagnosis, and Management.

Background: Tenosynovial giant cell tumor (TGCT), is a neoplasm arising from synovial joints, bursae, or tendon sheaths. The initial clinical symptoms are vague and non-diagnostic.

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In genetic studies of cerebrovascular diseases, the optimal vessels to use as controls remain unclear. Our goal is to compare the transcriptomic profiles among 3 different types of control vessels: superficial temporal artery (STA), middle cerebral arteries (MCA), and arteries from the circle of Willis obtained from autopsies (AU). We examined the transcriptomic profiles of STA, MCA, and AU using RNAseq.

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Quantitative descriptions of stream network and river catchment characteristics provide valuable context for enabling geomorphologically-informed sustainable river management. For countries where high-quality topographic data are available, there are opportunities to enable open access availability of baseline products from systematic assessment of morphometric and topographic characteristics. In this study, we present a national-scale assessment of fundamental topographic characteristics of Philippine river systems.

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Introduction: Positron emission tomography (PET) with prostate-specific membrane antigen (PSMA) improves prostate cancer staging. Furthermore, the intensity of intraprostatic uptake of PSMA can predict clinically relevant oncologic outcomes. The objective of this study is to evaluate whether the intensity of PSMA uptake is associated with clinically significant prostate cancer and to determine which value of PSMA uptake best discriminates this relationship.

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Background And Objectives: While somatic mutations have been well-studied in cancer, their roles in other complex traits are much less understood. Our goal is to identify somatic variants that may contribute to the formation of saccular cerebral aneurysms.

Methods: We performed whole-exome sequencing on aneurysm tissues and paired peripheral blood.

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Introduction: Psoas abscess is a rare pathological entity being retroperitonescopy an unusual therapeutic modality for its resolution.

Materials And Methods: The objective is to present and describe five patients with a diagnosis of psoas abscess that were resolved by retroperitoneoscopy in our institution and then carried out a non-systematic review of the literature.

Results: The mean age was 58.

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Objective: To analyze the trifecta results in patients with T1a and T1b renal tumors treated with retroperitoneoscopic partial nephrectomy (RPN).

Material And Methods: A cross-sectional prospective observational study was conducted on 106 patients with cT1 renal tumor submitted to RPN. Trifecta was reported as no ≥ 2 Clavien-Dindo complications, warm ischemia time (WIT) ≤ 25 minutes, ≤ 15% postoperative ΔGFR, and nonpositive margins.

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Geogrids are building materials widely used for soil reinforcement that can be affected by the action of many degradation agents throughout their service life. The potential negative effect of the degradation agents should be properly estimated and accounted for during the design phase. The main aim of this work was to study the influence of mechanical damage under repeated loading on the resistance of geogrids against abrasion.

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Vascular and infectious causes are rare but important causes of spinal cord injury. High suspicion for these processes is necessary, as symptoms may progress over hours to days, resulting in delayed presentation and diagnosis and worse outcomes. History and clinical examination findings can assist with localization of the affected vascular territory and spinal level, which will assist with focusing spinal imaging.

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Objectives: to understand the perceptions of senior students in an undergraduate nursing course at a nursing college in Lisbon regarding skills related to clinical decision-making learned during their initial training.

Methods: qualitative study, of an exploratory and descriptive nature. Data collection occurred by carrying out a focus group with eight senior students in an undergraduate nursing course.

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Introduction: Spontaneous bladder rupture is a rare condition, especially after a nontraumatic vaginal delivery.

Case Presentation: A 32-year-old patient who had had a nontraumatic vaginal delivery presented to the emergency room with abdominal pain and anuria. Computed tomography showed free fluid in the peritoneal cavity.

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Since its first description, laparoscopic adrenalectomy has become the gold standard for the surgical treatment of adrenal tumors. In patients who have previously undergone major transperitoneal or retroperitoneal surgeries, a retroperitoneal access through a virgin thoracic cavity might be the only alternative for a minimally invasive approach. We report a case of a 61-year-old man with a history of retroperitoneal nephrectomy caused by renal cell carcinoma.

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Introduction: The improvements in laparoscopic urological surgery have made laparoscopic adenomectomy (LA) possible in voluminous prostatic adenomas.

Objective: The objective of this study was to assess the results of the LA and compared them with results of the open adenomectomy (OA).

Material And Methods: A comparative study of 41 patients undergoing LA [23 LA with Millin technique (LA-MT) and 21 with transvesical technique (LA-TV)] was conducted with 44 patients undergoing OL in prostate adenomas > 100 grams.

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The installation process of geosynthetics can be, in some applications, one of the most relevant degradation mechanisms of these construction materials, affecting their performance and useful lifetime. In this work, three nonwoven geotextiles with different masses per unit area were submitted to mechanical damage under repeated loading tests with and with different natural aggregates. The damage occurred in the geotextiles was evaluated by visual inspection and by monitoring changes in their short-term tensile and puncture behaviors (mechanical properties) and in their water permeability behavior normal to the plane (hydraulic property).

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A major challenge for many industries wanting to adopt 3D printing technologies for rapid prototyping, customized parts, and low-volume manufacturing depends on the availability and functionality of the input materials to suit specific requirements. A well-studied nanofiller because of its distinct properties and wide range of applications, graphene oxide (GO) proves to be a good choice in the development of new materials. However, as a filler in a polymer matrix, GO has its own unique set of problems enough to make certain constraints in achieving an optimum reinforcement in the targeted polymer matrix.

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The behaviour of materials used for developing engineering structures should be properly foreseen during the design phase. Regarding geosynthetics, which are construction materials used in a wide range of engineering structures, the installation on site and the action of many degradation agents during service life may promote changes in their properties, endangering the structures in which they are applied. The evaluation of the damage suffered by geosynthetics, like installation damage or abrasion, is often carried out through laboratory tests.

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Objective: Surgical resection of sphenoid wing tumors and intraorbital pathology carries the dual goal of appropriately treating the target pathology as well as correcting proptosis. Residual proptosis following surgery can lead to cosmetic and functional disability. The authors sought to quantitatively assess the effect of orbital volume before and after reconstruction to determine the optimal strategy to achieve proptosis correction.

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Background: Digital subtraction angiography (DSA) is the gold standard for vascular imaging, but is not easily integrated into a continuous microsurgical environment. Other available modalities for intraoperative vascular assessment have their own limitations.

Objective: To investigate multispectral fluorescence (MFL), a new technology based on indocyanine green (ICG) fluorescence, which may provide advantages over current intraoperative imaging modalities.

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Importance: Tumor-treating fields (TTFields) therapy improves both progression-free and overall survival in patients with glioblastoma. There is a need to assess the influence of TTFields on patients' health-related quality of life (HRQoL).

Objective: To examine the association of TTFields therapy with progression-free survival and HRQoL among patients with glioblastoma.

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We characterized health-related quality of life (HRQoL), cognitive, and functional status in newly diagnosed glioblastoma (GBM) patients receiving Tumor treating fields (TTFields) with temozolomide (TMZ) versus TMZ alone in a planned interim analysis of a randomized phase III trial [NCT00916409], which showed significant improvement in progression-free and overall survival with TTFields/TMZ. After radiotherapy with concomitant TMZ, newly diagnosed GBM patients were randomized (2:1) to TTFields/TMZ (n = 210) or TMZ (n = 105). Interim analysis was performed in 315 patients with ≥18 months of follow-up.

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The Philippines is one of the most vulnerable countries in the world to the potential impacts of climate change. To fully understand these potential impacts, especially on future hydrological regimes and water resources (2010-2050), 24 river basins located in the major agricultural provinces throughout the Philippines were assessed. Calibrated using existing historical interpolated climate data, the STREAM model was used to assess future river flows derived from three global climate models (BCM2, CNCM3 and MPEH5) under two plausible scenarios (A1B and A2) and then compared with baseline scenarios (20th century).

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The number of endovascularly-treated aneurysms has steadily increased over the past two decades. A small but significant number of recurrent or partially recanalized aneurysms have been identified. If repeat endovascular therapies are not feasible due to anatomical or technical considerations, surgical clipping may be considered.

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Background: Arachnoid cysts and meningeal membranes are among the differential diagnostic considerations of extra-medullary causes of thoracic myelopathy. In this case series of 7 patients, we present compressive meningeal membranes mimicking dorsal arachnoid cyst. The propensity of the meningeal membranes for the dorsal aspect of upper thoracic spine may reflect derangements of the septum posticum.

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