Offense Narrative Roles of Turkish Offenders.

The study of offense narratives emphasizes the agency of the offender which brings psychology closer to law. As an effort to create a standardized and quantitative method to evaluate offender narratives, Youngs and Canter developed the Narrative Roles Questionnaire (NRQ) based on the content analyses of the crime narratives of offenders in UK prisons. The current study aims to investigate the applicability of offense narrative roles framework among Turkish offenders.

Themes of agency and communion and rehabilitation from substance misuse.

Background: Current models of identity transformation in substance misuse recovery emphasise either communal or agentic growth processes. Building on life narrative studies of addicted males, the present study proposes that agency and communion themes distinguish the narrative identities of rehabilitated substance users from active users.

Method: The 'Life as a Film' (LAAF) task was used to record narratives in an opportunity sample of 32 participants (23 males, 9 females) with ongoing or substance misuse history.

Systemic delivery of chTNT-3/CpG immunoconjugates for immunotherapy in murine solid tumor models.

CpG oligodeoxynucleotides (CpG) potently activate the immune system by mimicking microbial DNA. Conjugation of CpG to chTNT-3, an antibody targeting the necrotic centers of tumors, enabled CpG to accumulate in tumors after systemic delivery, where it can activate the immune system in the presence of tumor antigens. CpG chemically conjugated to chTNT-3 (chTNT-3/CpG) were compared to free CpG in their ability to stimulate the immune system in vitro and reduce tumor burden in vivo.

Criminal Narrative Experience: Relating Emotions to Offence Narrative Roles During Crime Commission.

A neglected area of research within criminality has been that of the experience of the offence for the offender. The present study investigates the emotions and narrative roles that are experienced by an offender while committing a broad range of crimes and proposes a model of criminal narrative experience (CNE). Hypotheses were derived from the circumplex of emotions, Frye, narrative theory, and its link with investigative psychology.

Key factors influencing ADME properties of therapeutic proteins: A need for ADME characterization in drug discovery and development.

Protein therapeutics represent a diverse array of biologics including antibodies, fusion proteins, and therapeutic replacement enzymes. Since their inception, they have revolutionized the treatment of a wide range of diseases including respiratory, vascular, autoimmune, inflammatory, infectious, and neurodegenerative diseases, as well as cancer. While in vivo pharmacokinetic, pharmacodynamic, and efficacy studies are routinely carried out for protein therapeutics, studies that identify key factors governing their absorption, distribution, metabolism, and excretion (ADME) properties have not been fully investigated.

Forgiveness-reconciliation and communication-conflict-resolution interventions versus retested controls in early married couples.

The first 6 months of marriage are optimal for marriage enrichment interventions. The Hope-Focused Approach to couple enrichment was presented as two 9-hr interventions--(a) Handling Our Problems Effectively (HOPE), which emphasized communication and conflict resolution, and (b) Forgiveness and Reconciliation through Experiencing Empathy (FREE). HOPE and FREE were compared with repeated assessment controls.

Cytoreductive chemotherapy improves the biodistribution of antibodies directed against tumor necrosis in murine solid tumor models.

Current strategies in cancer treatment employ combinations of different treatment modalities, which include chemotherapy, radiotherapy, immunotherapy, and surgery. Consistent with that approach, the present study demonstrates how chemotherapeutic agents can potentiate the delivery of radiolabeled, necrosis-targeting antibodies (chTNT-3, NHS76) to tumor. All chemotherapeutics in this study (5-fluorouracil, etoposide, vinblastine, paclitaxel, and doxorubicin) resulted in statistically significant increases in tumor uptake of radiolabeled antibodies and their F(ab')2 fragments compared to no pretreatment with chemotherapy.

Cognitive bias in line-up identifications: the impact of administrator knowledge.

Prior knowledge of the likely or expected outcome of a forensic investigation has been shown to produce biases in the results obtained, reducing objectivity. The wide prevalence of such cognitive biases in many judgments has long been recognised by social psychologists, but its importance is only now gaining appreciation within forensic science communities. It is therefore timely to draw attention to the power of cognitive biases found in a study of the influence of administrator expectations on photographic identifications.

Offenders' crime narratives as revealed by the Narrative Roles Questionnaire.

The study of narrative processes as part of the immediate factors that shape criminal action is limited by the lack of a methodology for differentiating the narrative themes that characterise specific crime events. The current study explores how the roles offenders see themselves as playing during an offence encapsulate their underlying crime narratives and thus provide the basis for a quantitative methodology. To test this possibility, a 33-item Narrative Roles Questionnaire (NRQ) was developed from intensive interviews with offenders about their experience of committing a recent offence.

Classifying homicide offenders and predicting their characteristics from crime scene behavior.

A theoretical distinction between instrumental and expressive aggression was used in analyzing offender characteristics and their associations with crime scene actions in Finnish homicides. Twenty-one variables reflecting the offenders' criminal activity, previous relationships with intimates and victims, and general social and psychological adjustment were derived from files of single-offender/single-victim homicides occurring between 1980 and 1994 (n = 502). Additionally, three variables describing post-offense actions and police interview behavior were included.

Narrative plausibility: the impact of sequence and anchoring.

The perceived plausibility of suspect narratives is hypothesized to be a product of more than logical evaluation. Aspects of the narrative's internal structure, notably the extent to which it follows a canonical (or stereotypical) sequence of events, may influence judged plausibility. Plausibility may also be sensitive to external "anchors" that activate relevant schema.

Predicting the home location of serial offenders: a preliminary comparison of the accuracy of human judges with a geographic profiling system.

The accuracy with which human judges, before and after 'training', could predict the likely home location of serial offenders was compared with predictions produced by a geographic profiling system known as Dragnet. All predictions were derived from ten spatial displays, one for each of ten different U.S.