Publications by authors named "David C Rosario"

Article Synopsis
  • The study aimed to determine normal levels of cardiac troponin-I in stable newborns and see how factors like maternal diabetes, delivery method, and Apgar scores influence these levels.
  • A total of 132 newborns were analyzed, with 119 for baseline troponin-I levels and 13 who were born to mothers with SARS-CoV-2.
  • Results showed a mean troponin-I level of 0.019 ± 0.018 ng/mL in healthy newborns, with no significant differences based on maternal health or delivery method, while those born to mothers with SARS-CoV-2 had higher levels at 0.081 ± 0.1 ng/mL.
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There has been a worldwide increase in cases of diabetic ketoacidosis in both adults and children with diabetes during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. This can be multifactorial: delayed care due to reduced medical services, fear of approaching hospitals, or SARS-CoV-2 infection itself. It is well-known that infection is an important trigger for diabetic ketoacidosis in children with type 1 or type 2 diabetes mellitus, but little is known whether SARS-CoV-2 infection can trigger diabetic ketoacidosis and new-onset diabetes mellitus in a child with no previous history of diabetes mellitus.

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Methaemoglobinaemia is a potentially life-threatening condition characterised by hypoxaemia, cyanosis, pallor, fatigue, metabolic acidosis, headache and in severe cases, coma or death. Topical anaesthetics have been reported to cause methaemoglobinaemia. Topical benzocaine was specifically implicated in roughly 66% of anesthetic-induced methaemoglobinaemia cases in a large systematic review in adults.

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