Publications by authors named "David C Marin"

Article Synopsis
  • The study assesses the effectiveness of the Enhanced Recovery after Stem-Cell Transplant (ER-SCT) program on survival rates for patients aged 65 and older undergoing hematopoietic stem-cell transplants (HSCT).
  • Results show that patients in the ER-SCT program had a significantly lower nonrelapse mortality (NRM) rate at 1 year (13%) compared to historical controls (26%) and a higher overall survival (OS) rate at 1 year (74% vs. 53%).
  • The findings suggest that multidisciplinary supportive care programs like ER-SCT could enhance outcomes for older adults in HSCT, prompting the need for further randomized studies to explore the specific benefits of different program elements.
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Targeting the gut microbiome as an effective therapeutic strategy for psychological disorders has shown promise in recent years. Variation in the composition of the microbiota and restoration of a stable microbiome using targeted interventions (psychobiotics) including Bifidobacteria have shown promise in pre-clinical studies, but more human data is required on the potential health benefits of these live microorganisms Bifidobacterium including 1714 has been shown to dampen the effects of acute stress in humans. However, its effects over a period of prolonged stress have not been examined.

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