Personalized Consent Flow in Contemporary Data Sharing for Medical Research: A Viewpoint.

Background: Health data personally collected by individuals with wearable devices and smartphones is becoming an important data source for healthcare, but also for medical research.

Objective: To describe a new consent model that allows people to control their personally collected health data and determine to what extent they want to share these for research purposes.

Methods: We developed, in close collaboration with patients, researchers, healthcare professionals, privacy experts, and an accredited Medical Ethical Review Committee, an innovative concept called "personalized consent flow" within a research platform connected to a personal health record.

Cortical thickness is associated with gait disturbances in cerebral small vessel disease.

Although gait disturbances are present in a substantial portion of patients with cerebral small vessel disease (SVD), their pathogenesis has not been clarified as they are not entirely explained by the white matter lesions (WMLs) and lacunar infarcts. The role of cortical thickness in these patients remains largely unknown. We aimed to assess the regions of cortical thickness associated with distinct gait parameters in patients with SVD, and whether these associations were dependent on WMLs and lacunar infarcts.