Vision impairment with an interstitial deletion of the short arm of chromosome 8.

We describe the phenotype of a male infant with an interstitial deletion of the short arm of chromosome 8 (p. 11.2-p.

Neoplastic transformation of ciliary body epithelium is associated with loss of opticin expression.

Background: Opticin is a recently discovered glycoprotein present predominantly in the vitreous humour. It is synthesised and secreted by the ciliary body epithelium (CBE) from the initiation of CBE development in the embryo, and production continues throughout life.

Aim: To determine whether a variety of ciliary body tumours synthesise opticin to characterise further its role in ciliary body health and disease.