Control of metal ion size-based selectivity through chelate ring geometry. metal ion complexing properties of 2,2'-biimidazole.

Some metal ion complexing properties of 2,2'-biimidazole (BIM) are presented. The ligand BIM forms minimum steric strain complexes with hypothetical metal ions with M-N (metal-nitrogen) bond lengths of 4.2 A, in contrast to more usual ligands such as bipy (2,2'-bipyridyl) that prefer metal ions with M-N bond lengths of 2.

Refinements in husbandry, care and common procedures for non-human primates: Ninth report of the BVAAWF/FRAME/RSPCA/UFAW Joint Working Group on Refinement.

Preface Whenever animals are used in research, minimizing pain and distress and promoting good welfare should be as important an objective as achieving the experimental results. This is important for humanitarian reasons, for good science, for economic reasons and in order to satisfy the broad legal principles in international legislation. It is possible to refine both husbandry and procedures to minimize suffering and improve welfare in a number of ways, and this can be greatly facilitated by ensuring that up-to-date information is readily available.