High-resolution crystal structure of the double nitrate hydrate [La(NO)][Ni(HO)]·6HO.

This study introduces bis-[hexa-kis-(nitrato-κ ,')lanthanum(III)] tris-[hexa-aqua-nickel(II)] hexa-hydrate, [La(NO)][Ni(HO)]·6HO, with a structure refined in the hexa-gonal space group . The salt com-prises [La(NO)] icosa-hedra and [Ni(HO)] octa-hedra, thus forming an intricate network of inter-penetrating honeycomb lattices arranged in layers. This arrangement is stabilized through strong hydrogen bonds.

Leptomeningeal Dissemination Complicated With Acute Tetraplegia From a Supratentorial Multicentric Isocitrate Dehydrogenase (IDH)-Wildtype Glioblastoma: A Case Report.

Glioblastoma (GBM) is a major concern for neurosurgeons and oncologists, being a malignant tumor with a high recurrence rate and reduced survival. Leptomeningeal dissemination (LMD) of GBM is rare and difficult to diagnose due to the low rate of cellular detection in the cerebrospinal fluid and clinical and imaging similarities with fungal and tuberculous meningitis. We report the case of a 25-year-old female patient suffering from multicentric GBM who developed hydrocephalus and extensive LMD three months after surgery for a left frontal parafalcine cerebral GBM isocitrate dehydrogenase (IDH)-wildtype.

Ba(IO): crystal structure evolution from room temperature to 80 K.

The crystal structure of Ba(IO), penta-barium bis-(orthoperiodate), has been re-investigated at room temperature based on single-crystal X-ray diffraction data. In comparison with a previous crystal structure determination by the Rietveld method, an improved precision of the structural parameters was achieved. Additionally, low-temperature measurements allowed the crystal structure evolution to be studied down to 80 K.

Substrate-Dependent Modulation of SIRT2 by a Fluorescent Probe, 1-Aminoanthracene.

Sirtuin isoform 2 (SIRT2) is an enzyme that catalyzes the removal of acyl groups from lysine residues. SIRT2's catalytic domain has a hydrophobic tunnel where its substrate acyl groups bind. Here, we report that the fluorescent probe 1-aminoanthracene (AMA) binds within SIRT2's hydrophobic tunnel in a substrate-dependent manner.

New refinement of the crystal structure of Zn(NH)Cl at 100 K.

The crystal structure of [ZnCl(NH)], diamminedi-chlorido-zinc, was re-investigated at low temperature, revealing the positions of the hydrogen atoms and thus a deeper insight into the hydrogen-bonding scheme in the crystal packing. In comparison with previous crystal structure determinations [MacGillavry & Bijvoet (1936 ▸). , 249-255; Yamaguchi & Lindqvist (1981 ▸).

Cationic PCP iridaepoxide and carbene complexes for facile water elimination and activation processes.

Iridaepoxide dihydride complexes of a PCP ligand bearing benzo[b]thiophene linkers are synthesized through ligand coopertive NO and H activations. These neutral complexes also eliminate water at elevated temperatures to form the corresponding PCP complexes which results in the formal hydrogenation of NO to water. The synthesis of cationic iridaepoxide dihydride complexes are reported herein where the room temperature elimination of water is observed when a donating solvent is used.

Activation of Si-H bonds across the nickel carbene bond in electron rich nickel PC(carbene)P pincer complexes.

Silicon-hydrogen bonds are shown to add to a nickel carbon double bond to yield nickel α-silylalkyl hydrido complexes. Kinetic and isotope labeling studies suggest that a concerted 4-centred addition across the Ni=C bond is operative rather than a mechanism involving Si-H oxidative addition. This constitutes an example of Si-H bond activation via ligand cooperativity.

The pulmonary histopathology of anti-KS transfer RNA synthetase syndrome.

Context: The clinical spectrum of the antisynthetase syndromes (AS) has been poorly defined, although some frequently present with pulmonary manifestations. The anti-KS anti-asparaginyl-transfer RNA synthetase syndrome is one in which pulmonary interstitial lung disease is almost always present and yet the histopathologic spectrum is not well described.

Objective: To define the morphologic manifestations of pulmonary disease in those patients with anti-KS antiasparaginyl syndrome.

The pulmonary histopathologic manifestations of the anti-PL7/antithreonyl transfer RNA synthetase syndrome.

The pulmonary histopathologic manifestations of the antisynthetase syndromes is poorly understood and reported. Eight cases of interstitial lung disease related to the presence of antitheonyl (PL7) transfer RNA synthetase autoantibodies along with a review of biopsy changes reported in the English literature are described. Most patients presented with dyspnea and cough, with myositis, skin changes including "mechanic's hands," and Raynaud phenomenon.