UVA-photoactivated riboflavin treatment of vaginal cells derived from pelvic organ prolapse cases.

Background: The pathophysiology of pelvic organ prolapse (POP) involves vaginal collagen degradation. Strengthening collagen by UVA-photoactivated cross-linking has been demonstrated and suggested target applications include the vaginal wall.

Aim: To identify UVA irradiation and riboflavin effects on vaginal cells.