Publications by authors named "David B Hogan"

The Canadian Consortium on Neurodegeneration in Aging (CCNA) was created by the Canadian federal government through its health research funding agency, the Canadian Institutes for Health Research (CIHR), in 2014, as a response to the G7 initiative to fight dementia. Two five-year funding cycles (2014-2019; 2019-2024) have occurred following peer review, and a third cycle (Phase 3) has just begun. A unique construct was mandated, consisting of 20 national teams in Phase I and 19 teams in Phase II (with research topics spanning from basic to clinical science to health resource systems) along with cross-cutting programs to support them.

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Objectives: Resident pain has been a common quality challenge in congregate care for older adults, and organizational context may explain variations in resident pain beyond resident-level factors. Most studies have focused on nursing homes (NHs), largely neglecting assisted living (AL). AL residents are at similar risk for pain as NH resident, but with AL providing fewer services and staffing resources.

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While the contributions of Dr Marjory W. Warren to geriatric medicine are widely acknowledged, their specifics have become obscured by the passage of time. The primary objective of this narrative review of her medical publications was to clarify the contributions she made for this field of medical practice.

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Background: Assisted living (AL) is an increasingly common residential setting for persons with dementia; yet concerns exist about sub-optimal care of this population in AL given its lower levels of staffing and services. Our objectives were to (i) examine associations between AL setting (dementia care vs. other), COVID-19 pandemic waves, and prevalent antipsychotic, antidepressant, anti-dementia, benzodiazepine, and anticonvulsant drug use among residents with dementia/cognitive impairment, and (ii) explore associations between resident and home characteristics and prevalent medication use.

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Article Synopsis
  • The study examined the prevalence and impact of 12 modifiable risk factors for dementia among middle-aged and older Canadians, using data from a large sample of 30,097 adults aged 45 to 85.
  • Key findings included high rates of physical inactivity, hypertension, and obesity, with physical inactivity being the most significant contributor to dementia risk.
  • The research emphasizes the need for tailored dementia prevention strategies in Canada, as socioeconomic status influenced the prevalence of risk factors and their potential impact on dementia cases.
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  • A study examined how COVID-19 affected hospitalization rates for older adults in assisted living (AL) compared to nursing homes (NH) during different pandemic waves in Alberta, Canada.
  • Results showed that hospitalization rates decreased in both AL and NH during waves 1 and 4, but AL did not experience a decline during wave 2, unlike NH.
  • The findings indicated that while NH residents faced more delayed hospital discharges, AL residents had a significant increase in hospitalizations that resulted in death, particularly during wave 2.
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Environmental factors resulting from climate change and air pollution are risk factors for many chronic conditions including dementia. Although research has shown the impacts of air pollution in terms of cognitive status, less is known about the association between climate change and specific health-related outcomes of older people living with dementia. In response, we outline a scoping review protocol to systematically review the published literature regarding the evidence of climate change, including temperature and weather variability, on health-related quality of life, morbidity, mobility, falls, the utilization of health resources, and mortality among older adults living with dementia.

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Objectives: Assisted living (AL) is a significant and growing congregate care option for vulnerable older adults designed to reduce the use of nursing homes (NHs). However, work on excess mortality in congregate care during the COVID-19 pandemic has primarily focused on NHs with only a few US studies examining AL. The objective of this study was to assess excess mortality among AL and NH residents with and without dementia or significant cognitive impairment in Alberta, Canada, during the first 2 years of the COVID-19 pandemic, relative to the 3 years before.

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Article Synopsis
  • The increasing prevalence of neurocognitive disorders (NCDs), such as mild cognitive impairment and dementia, highlights the urgent need for global prevention strategies.
  • An umbrella review synthesized findings from 45 reviews and 212 meta-analyses, identifying 14 modifiable risk factors linked to NCDs, including alcohol consumption, depression, and physical inactivity.
  • The study emphasizes the need for targeted prevention efforts that address these risk factors to reduce the incidence and severity of NCDs, particularly noting gaps in research related to vascular dementia and mild NCD.
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  • Recent research shows a potential connection between obstructive sleep apnea and cognitive decline, but the exact reasons behind this link are not fully understood.
  • The study involved 125 middle-aged and older adults, evaluating their sleep patterns and cognitive function, which included analyzing sleep spindles during specific sleep stages using polysomnography.
  • Findings indicated that the characteristics of sleep spindles were more closely related to certain verbal fluency scores rather than severity of obstructive sleep apnea, suggesting that biological sex may also influence these relationships.
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  • The study investigates the impact of COVID-19 pandemic waves on the use of various medications among residents in assisted living facilities in Alberta, Canada, focusing on differences between dementia care and other settings.
  • Researchers analyzed data from January 2018 to December 2021, revealing significant increases in antipsychotic use during pandemic waves, particularly among residents in dementia care, as well as modest increases in antidepressant use.
  • Overall, while some medication use increased or decreased during the pandemic, opioid use did not show significant changes, highlighting varied medication management responses in different assisted living settings.
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  • The study investigates the impact of social participation on the health of older adults (65+) in both rural and urban environments, highlighting the complex relationship between social activity, personal factors, and the surrounding environment.
  • Using data from the Canadian Longitudinal Study on Aging, the researchers measured how often participants engaged in various social activities and analyzed how neighborhood characteristics influenced their social participation.
  • Findings show that while the frequency of social participation was similar across settings, the types of activities varied; urban individuals favored sports and cultural events, while rural participants were more involved in service club activities, with transport and a sense of safety significantly impacting participation levels.
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Background: While assisted living (AL) and nursing home (NHs) residents in share vulnerabilities, AL provides fewer staffing resources and services. Research has largely neglected AL, especially during the COVID-19 pandemic. Our study compared trends of practice-sensitive, risk-adjusted quality indicators between AL and NHs, and changes in these trends after the start of the pandemic.

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Importance: Continuous bedside pressure mapping (CBPM) technology can assist in detecting skin areas with excessive interface pressure and inform efficient patient repositioning to prevent the development of pressure injuries (PI).

Objective: To evaluate the efficacy of CBPM technology in reducing interface pressure and the incidence of PIs.

Design, Setting, And Participants: This parallel, 2-group randomized clinical trial was performed at a tertiary acute care center.

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Background: Data on Canadian pharmacists' knowledge and perceptions about frailty in older adults and its assessment in pharmacy practice are scarce.

Methods: A cross-sectional survey of 349 Canadian pharmacists was conducted to evaluate pharmacists' knowledge, perceptions and practices regarding frailty. Descriptive analyses summarized responses by practice setting, and a multivariable logistic regression model examined associations between respondent characteristics and the likelihood of assessing frailty.

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Concerns (or 'fears') about falling (CaF) are common in older adults. As part of the 'World Falls Guidelines Working Group on Concerns about Falling', we recommended that clinicians working in falls prevention services should regularly assess CaF. Here, we expand upon these recommendations and argue that CaF can be both 'adaptive' and 'maladaptive' with respect to falls risk.

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Introduction: Family/friend caregivers play an essential role in promoting the physical and mental health of older adults in need of care - especially during the COVID-19 pandemic and especially in assisted living (AL) homes, where resident care needs are similarly complex as in long-term care homes but fewer staffing resources and services are available. However, little research is available on caregiver involvement and concerns with care of AL residents prior to and during waves 1 and 2 of the COVID-19 pandemic. This study addressed this important knowledge gap.

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Background: Accessible measures specific to the Canadian context are needed to support health system planning for older adults living with frailty. We sought to develop and validate the Canadian Institute for Health Information (CIHI) Hospital Frailty Risk Measure (HFRM).

Methods: Using CIHI administrative data, we conducted a retrospective cohort study involving patients aged 65 years and older who were discharged from Canadian hospitals from Apr.

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Article Synopsis
  • The study investigates trends in the concurrent use of opioids with benzodiazepines (BZDs) and gabapentinoids among nursing home residents in Ontario from 2009 to 2020.
  • It found a significant decrease in BZD use alongside opioids (from 30.7% to 14.4%) while gabapentinoid use increased dramatically (from 4.4% to 26.6%).
  • Factors influencing concurrent use varied, with older age and cognitive decline linked to lower use, while sex and anxiety disorders were associated with BZDs, and pain severity with gabapentinoids.
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Objectives: This study aims to develop and validate a Bayesian risk prediction model that combines research cohort data with elicited expert knowledge to predict dementia progression in people with mild cognitive impairment (MCI).

Study Design And Setting: This is a prognostic risk prediction modeling study based on cohort data (Alzheimer's disease neuroimaging initiative [ADNI]; n = 365) of research participants with MCI and elicited expert data. Bayesian Cox models were used to combine expert knowledge and ADNI data to predict dementia progression in people with MCI.

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Article Synopsis
  • - This study evaluates what experts believe are the key risk factors that can lead to dementia in individuals with mild cognitive impairment (MCI).
  • - Ten experts, including neurologists, geriatricians, and psychiatrists, participated in structured meetings and surveys to identify the top predictors of dementia progression, such as age, brain imaging results, and cognitive assessment scores.
  • - The findings suggest that many important predictors of dementia are not regularly collected in current healthcare practices, which may contribute to the limited use of published dementia risk assessment tools in clinical settings.
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Background: Science is becoming increasingly data intensive as digital innovations bring new capacity for continuous data generation and storage. This progress also brings challenges, as many scientific initiatives are challenged by the shear volumes of data produced. Here we present a case study of a data intensive randomized clinical trial assessing the utility of continuous pressure imaging (CPI) for reducing pressure injuries.

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Problem: Complex brain disorders involve symptoms in the domains of affect, behavior, and cognition. It is increasingly recognized that there is a need for a novel type of physician who can treat individuals with these conditions in an interdisciplinary fashion to best address their complexity. Few training programs have focused on the education of such practitioners.

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Objectives: To examine the prevalence of coping behaviors during the first 2 waves of the COVID-19 pandemic among caregivers of assisted living residents and variation in these behaviors by caregiver gender and mental health.

Design: Cross-sectional and longitudinal survey.

Setting And Participants: Family/friend caregivers of assisted living residents in Alberta and British Columbia.

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