Using the Design Thinking Approach for a University Health Promotion Program: A Pilot Study.

University wellness programs often employ health campaigns to promote awareness and engagement in health behaviors. However, with limited resources, it is challenging to develop and test health campaign materials in a timely manner. The Design Thinking Approach (DTA) provides a promising strategy for developing materials in a quicker, less expensive way compared to traditional methods.

Alterations in mGluR5 expression and signaling in Lewy body disease and in transgenic models of alpha-synucleinopathy--implications for excitotoxicity.

Dementia with Lewy bodies (DLB) and Parkinson's Disease (PD) are neurodegenerative disorders of the aging population characterized by the abnormal accumulation of alpha-synuclein (alpha-syn). Previous studies have suggested that excitotoxicity may contribute to neurodegeneration in these disorders, however the underlying mechanisms and their relationship to alpha-syn remain unclear. For this study we proposed that accumulation of alpha-syn might result in alterations in metabotropic glutamate receptors (mGluR), particularly mGluR5 which has been linked to deficits in murine models of PD.