Publications by authors named "David Andrew Fitzmaurice"
J Am Coll Cardiol
September 2020
Article Synopsis
- A study analyzed the impact of prescribed doses of direct oral anticoagulants (DOACs) on health outcomes in patients with atrial fibrillation over a 2-year period, focusing on mortality and stroke/systemic embolism risks.
- Out of nearly 35,000 patients in the GARFIELD-AF registry, 72.9% received recommended dosing, while 23.2% were underdosed and 3.8% overdosed; nonrecommended dosing was linked to a higher risk of all-cause mortality, particularly from cardiovascular issues.
- The findings highlighted that although underdosed patients faced lower bleeding risks, the differences in stroke/systemic embolism and major bleeding risks were not statistically significant among
