Aqueous graphene dispersions-optical properties and stimuli-responsive phase transfer.

We demonstrate essentially complete exfoliation of graphene aggregates in water at concentrations up to 5% by weight (166-fold greater than previous high concentration report) using recently developed triblock copolymers and copolymeric nanolatexes based on a reactive ionic liquid acrylate surfactant. We demonstrate that the visible absorption coefficient in aqueous dispersion, 48.9 ± 1.

Consumption of dried apple peel powder increases joint function and range of motion.

The goal for this study was to evaluate the effects of consumption of dried apple peel powder (DAPP) on joint function and range of motion (ROM). Additional in vitro and clinical testing was performed to suggest specific mechanisms of action. An open-label clinical pilot study involved 12 healthy people with moderate loss of joint ROM and associated chronic pain.

Improvement of joint range of motion (ROM) and reduction of chronic pain after consumption of an ergothioneine-containing nutritional supplement.

Objective: To evaluate anti-inflammatory properties of a nutraceutical blend containing L-ergothioneine in concert with other anti-inflammatory and analgesic ingredients, combined with nutritional cartilage support.

Methodology: Twelve human subjects were tested over a 6-week period of product consumption followed by a 6-week wash-out period, conducted at NIS Labs during late fall/early winter 2010. Range of motion (ROM) assessment of joint motility was performed using JTECH dual digital inclinometry and included flexion, extension, and rotation through the vertical weight-bearing column (neck, thorax, lumbar, hip, knees) and shoulders.

Asymmetric homogeneous hydrogenations at scale.

Asymmetric hydrogenations are increasingly being used to introduce stereogenic centres into products used in the life sciences industries. There are a number of potential pitfalls when moving from a laboratory reaction to a manufacturing process, not least of which is safety. Time-to-market pressure leads to short development times, which in the past could be a large barrier for the implementation of catalytic steps; now there are new ways to minimise this problem.

Pain reduction and improvement in range of motion after daily consumption of an açai (Euterpe oleracea Mart.) pulp-fortified polyphenolic-rich fruit and berry juice blend.

Dietary interventions involving antioxidants are of interest for reducing inflammation, improving joint motion, and altering pain perception. We evaluated the effect of oral consumption of a fruit and berry blend on pain and range of motion (ROM). This open-label clinical pilot study involved 14 study participants with limitations in ROM that was associated with pain and affected daily living.

Asymmetric hydrogenation and other methods for the synthesis of unnatural amino acids and derivatives.

New methods to unnatural amino acids continue to be developed. This review covers methods, published in 2001, that employ an asymmetric hydrogenation, a transition metal-catalyzed reaction, an enzymatic resolution or a chiral auxiliary.

New developments in the Peterson olefination reaction.

Noteworthy developments of the Peterson olefination reaction are reviewed. Evidence for both concerted and stepwise mechanisms for the Peterson olefination reaction is presented. The strong affinity of the oxygen anion for the silyl moiety is emphasised when the Peterson olefination reaction takes preference over both the Julia and Wittig reactions in the presence of S- and P-stabilised silyl carbanions.