Is an atypical presentation becoming typical of coeliac disease?

A 38-year-old woman was referred to a gastroenterology clinic for investigation of abnormal liver function test (LFT). She had no history of pre-existing liver disease, diabetes mellitus, hypertension, excess alcohol consumption or use of any hepatotoxic drugs. She was being investigated and treated by oral surgeons for recurrent mouth ulcers which she had for about 18 months.

Mechanisms of hypertension after liver transplantation.

Hypertension is the most common cardiovascular complication after liver transplantation. Systemic vasoconstriction underlies transplant hypertension, but the mechanisms contributing to this remain unresolved. Plasma renin, aldosterone, and endothelin (ET)-1 together with augmentation index, a measure of arterial stiffness, were determined before and at intervals of 1, 3, and 6 months after transplant in 32 consecutive patients accepted for liver transplantation.

Hemodynamic effects of amlodipine, bisoprolol, and lisinopril in hypertensive patients after liver transplantation.

Background: Hypertension is common after liver transplantation. There are few published data on optimum treatment. Augmentation index (AIx) is a measure of arterial wave reflection determined by pulse wave analysis.

Is there disparity between risk and incidence of cardiovascular disease after liver transplant?

Background: Hypertension and hypercholesterolemia are recognized complications of liver transplantation, but whether they contribute to the development of cardiovascular disease is uncertain. We aimed first to determine the prevalence of risk factors for coronary heart disease (CHD) after liver transplantation and second to study the effect of liver transplantation on the predicted 10-year risk of developing CHD and the incidence of cardiovascular events in comparison with a matched local population.

Methods: Data on blood pressure, serum lipids, weight, diabetes mellitus, smoking, and incidence of myocardial infarction (MI) and stroke were obtained retrospectively from the case notes of 181 consecutive adult liver transplant recipients (median follow-up 54 months).